Post-exposure #prophylaxis with #favipiravir among #household close contacts to confirmed #COVID19 cases: A cluster-randomized trial (PEPfavi), https://etidiohnew.blogspot.com/2026/02/post-exposure-prophylaxis-with.html
Post-exposure #prophylaxis with #favipiravir among #household close contacts to confirmed #COVID19 cases: A cluster-randomized trial (PEPfavi)

last year's feature about the breakthrough in long-lasting #prophylaxis against #HIV-#AIDS is now in the #openArchive https://www.cell.com/current-biology/fulltext/S0960-9822(24)01500-8
#science #medicine #health #publicHealth
Prophylactic progress against AIDS

Successful clinical trials of a long-lasting prophylaxis against HIV infection and a promise to make it accessible in poorer countries may mark a turning point in fighting the ongoing AIDS pandemic. However, the stigma and complexities surrounding the disease could complicate matters, while the development of effective vaccines remains a struggle.

Current Biology
Post-exposure #prophylaxis regimen of #rabies monoclonal #antibody and #vaccine in category 3 potential exposure patients ..., https://etidiohnew.blogspot.com/2025/08/post-exposure-prophylaxis-regimen-of.html
Post-exposure #prophylaxis regimen of #rabies monoclonal #antibody and #vaccine in category 3 potential exposure patients ...

Before the case was narrowed to the #AppointmentsClause issue, the lawsuit included a #religious objection to being required to cover pre-exposure #prophylaxis for #HIV. They claimed that such drugs "facilitate & encourage homosexual behavior, prostitution, sexual promiscuity & intravenous drug use."

#law #SCOTUS #medicine #HealthCare #ACA #insurance #PreventiveCare

Lenacapavir: this annual shot might protect against HIV infections
https://www.technologyreview.com/2025/03/14/1113225/annual-shot-protect-against-hiv

[Dec 2024] Drug lenacapavir 'breakthrough of year.' Could end HIV epidemic
https://mastodon.social/@persagen/113643639851357794
https://en.wikipedia.org/wiki/Lenacapavir

Promising results from an early-stage trial suggest that lenacapavir injections might offer long-lasting protection.

Comment: the value of basic science/biomedical research cannot be emphasized enough.

#HIV #AIDS #prophylaxis #lenacapavir
#GileadScience #PURPOSE1 #PURPOSE2 studies

This annual shot might protect against HIV infections

Promising results from an early-stage trial suggest that lenacapavir injections might offer long-lasting protection.

MIT Technology Review
Evaluation of #influenza #antiviral #prophylaxis for long-term care residents: a systematic review and meta-analysis, https://etidiohnew.blogspot.com/2025/03/evaluation-of-influenza-antiviral.html
Evaluation of #influenza #antiviral #prophylaxis for long-term care residents: a systematic review and meta-analysis

Pre-exposure #antibody #prophylaxis protects #macaques from severe #influenza

Drug lenacapavir 'breakthrough of year.' Could end HIV epidemic
https://www.npr.org/sections/goats-and-soda/2024/12/12/g-s1-37662/breakthrough-hiv-lenacapavir

* 1.3M new HIV infect./yr globally
* U.N. goal: end HIV/AIDS by 2030
* 2 groundbreaking clinical trials
* drug lenacapavir virt. elim. new HIV infections thru sex
* Science j. 2024 Breakthrough of Year
* admin. via 2x yearly injection

Lenacapavir: https://en.wikipedia.org/wiki/Lenacapavir

Epidemiology of HIV/AIDS
https://en.wikipedia.org/wiki/Epidemiology_of_HIV/AIDS

#HIV #AIDS #prophylaxis #lenacapavir
#GileadScience #PURPOSE1 #PURPOSE2 studies

I repeat: hypochlorous acid is a miracle. HOCl solution can apparently be nebulized and inhaled as a prophylactic (CW: animal testing)

"In this report, we establish through independent laboratories that the SARS-CoV-2 virus is rapidly inactivated by exposure to HOCl, as is poliovirus – a far more difficult virus to inactivate and often the gold standard for virucidal assessment. Inhalation of a microaerosolized fog of that same virucidal HOCl solution by rodents using the US EPA’s acute 4-hour inhalation toxicity protocol later provided observational, physiological, gross pathological, and histopathological evidence that showed pulmonary exposure of 52ppm HOCl to respiratory epithelium did not result in any difference when compared to control animals. Also reported are the chemical and antimicrobial characterizations of the HOCl microaerosols reportedly used as SARS-CoV-2 prophylaxis within the United States and elsewhere during the pandemic lockdown."

This also implies that you could stick it in a humidifier and disinfect the air of a space that someone infectious may have recently left, in addition to (or as an alternative to, if unavailable) air filtration

https://fortuneonline.org/articles/inhalation-of-microaerosolized-hypochlorous-acid-hocl-biochemical-antimicrobial-and-pathological-assessment.html

#SARSCoV2 #covid #covid19 #prophylactic #prophylactics #prophylaxis #PublicHealth #CovidIsNotOver

Inhalation of Microaerosolized Hypochlorous Acid (HOCl): Biochemical, Antimicrobial, and Pathological Assessment

Inhalation of Microaerosolized Hypochlorous Acid (HOCl): Biochemical, Antimicrobial, and Pathological Assessment. PubMed, SCI, Scopus, ESCI, PMC indexed