Pregnenolone promotes immune evasion through blocking endogenous #retrovirus expression.

Sexual abstinence promotes #tumor progression by inducing #pregnenolone production. Pregnenolone facilitates the formation of H3K9me3 to suppress #ERV replication.

https://www.sciencedirect.com/science/article/abs/pii/S1550413125005844 #microbiology #cancer

Any #science #endocrinology #doctor types or knowledgeable patients out there?

Have some questions before I spend money I don’t have re #DHEA & #pregnenolone.:

I’m trying to find a good compounding chemist in #Melbourne #Ausralia to compound DHEA (it’s illegal in Aus to buy off the shelf, need compounding prescription & permit- got both).

BUT! I’m getting confused by the chemists. Some say I must get a DHEA troche or a capsule will convert straight to #estrogen or #testosterone, no chance to tap DHEA receptors (unsure if they exist). I’ve also read it modulated other receptors before being metabolised.Wouldn’t I be better off w a cream in that case? Other compounders say there’s no difference. BS?

I thought #pregnenolone
might help more. It’s the ‘mother hormone’, right?
Since I caught #COVID19 I’m mostly producing low hormones but it varies. Cortisol normalised, still on thyroid meds, oestrogen shot up, no DHEA or testosterone…plus much more going on.

#MedMastodon
@medmastodon

Any #science #endocrinology #doctor types out there?

Have some questions before I spent money I don’t have:

#DHEA: Can anyone w science background/knowledgeable patient help with this?
I’m trying to find a good compounding chemist (DHEA illegal in Aus without compounding prescription & permit- got both)

BUT! I’m getting confused by the chemists. Some say I must get a DHEA troche or will convert straight to #estrogen or #testosterone as capsule, no chance to tap DHEA receptors. Ive also read it taps & modulates other receptors beforehand. Wouldn’t I be better off w a cream in that case? Other compounders say there’s no difference. BS? Halp.

I thought #pregnenolone might help more. It’s the ‘mother hormone’, right?
Since I caught #COVID19 I’m mostly producing low #hormones but it can varies (some up, others down, some normalise after a time. Cortisol normalised, still on thyroid meds, oestrogen shot up, no DHEA or testosterone… much more.

Can anyone help? I’ve been through multiple doctors, asked pharmacist and they all contradict themselves and each other or don’t know what either home does.

Don’t ever get #ChronicIllness

You’ll up relying on people who don’t know how medicine works. Very few knowledgeable people.

#MedMastodon
@medmastodon