Sometimes you wonder why the labs with all the funding (not just this one! This is just one example) do not do slightly more risky experiments instead of rediscovering the wheel.. 🤔 This is something anyone who records in hippocampus has observed and there's even specific papers about it.

Place cells in CA1 lack topographical organization of firing locations

See for example Redish et al., 2001: Independence of Firing Correlates of Anatomically Proximate Hippocampal Pyramidal Cells from @adredish (at least it is cited)

#PlaceCells #Hippocampus #SpatialCognition

Which of these famous "spatial cell" type is better?

Well, which is your favourite anyway? Yes it's a silly question

#SillyPoll #Neuroscience #PlaceCells #GridCells #BorderCells #BVCs #HeadDirectionCells

Here's a very interesting paper from the #KeinathLab:

Environmental representations in mouse hippocampal CA1 reflect the predictive structure of navigation

In the absence of task or reward, #PlaceCells appear to reflect the past history of behavioural biases, i.e. the accumulated past paths taken by each individual mouse. I am actually starting to think that #HippocampalReplay is doing a similar thing - just reflecting an average of the individual's past behaviour, and that all supposed "coding" of reward is purely driven by this (notice how reward "coding" always seems to happen in cases where reward biases the behavioural patterns..) 👀🧠🤔

#Neuroscience #Hippocampus #NeuroMice

Very cool retrospective AND review of the hippocampal #SpatialCognition field from Neil Burgess:
Oscillations and Boundaries in My Route Through the Hippocampal Cognitive Map

Mentions @adredish @tom_hartley and many others, unfortunately not on Mastodon I think
#Neuroscience #PlaceCells #GridCells #Hippocampus #ThetaRhythm

📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.

🌍 https://www.nature.com/articles/s41593-025-01986-3

#Hippocampus #Neuroscience

Heading off to the #EBBS2025 conference in Bordeaux!
I will present a poster there on our latest #HippocampalReplay findings (replay does not do planning, but seems to support reward-learning instead, in a flexible spatial planning task), and co-lead a symposium with the great John Widloski, also on replay!
We have an amazing speaker list with John himself, Lisa Genzel, Jacob Bakermans and Elisa Massi!

Check the full programme here: https://ebbs2025.azuleon.org/programme_overview

Will you be there?!

#Neuroscience #NeuroConf #PlaceCells #Hippocampus

#PlaceCells often have elongated place fields next to an environment's boundaries.
Is there any paper where this phenomenon is directly predicted by the #SuccessorRepresentation model of place cells?

#SpatialCognition #Neuroscience #Hippocampus

Thinking about #PlaceCells and the #Hippocampus, do you think results in rats (/rodents) generalise well to humans, and conversely?

#Neuroscience #NeuroRat #NeuroHuman