katch wreckApr 8, 2024
"NeuM micelles were selectively internalized into neuronal endosomes via clathrin-mediated endocytosis..NeuM micelles integrate into neuronal membrane, dispersing fluorescent NeuM molecules in the membrane..simulations demonstrated that NeuM..possesses optimal lipophilicity & molecular length, facilitating its stable incorporation into #phospholipid layers..stable integration..allows..prolonged monitoring of #neurons, as well as the visualization of intricate..structures" https://onlinelibrary.wiley.com/doi/10.1002/anie.202312942
Journal of Experimental BotanySep 12, 2023

'Phosphatidylinositol-phospholipase C3 negatively regulates the #hypersensitive response via complex signaling with #MAPkinase, #phytohormones, and reactive oxygen species in Nicotiana benthamiana'

https://doi.org/10.1093/jxb/erad184

#JasmonicAcid #ROS #SalicylicAcid #GeneSilencing #Phospholipid

Phosphatidylinositol-phospholipase C3 negatively regulates the hypersensitive response via complex signaling with MAP kinase, phytohormones, and reactive oxygen species in Nicotiana benthamiana

In Nicotiana benthamiana, PLC3-1 and -2 complement each other during the hypersensitive response to negatively regulate and fine tune the response through sever

OUP Academic
The EMBO JournalJul 17, 2023

Issue 14:
Highlight on #ROR1 and #pancreatic #malignancy

Review on viral recognition and #antiviral #interferon response

#Autophagy news from plants and mammals
How #p97 disassembles a regulatory protein complex
Developmental #axon pruning by a #phospholipid #scramblase

Cover: Elisa Nerli, Caren Norden and colleagues

https://www.embopress.org/toc/14602075/2023/42/14

The EMBO JournalMay 22, 2023
What fine-tunes #mammalian brain connectivity during #development?
Urtė Neniškytė, Cornelius Gross et al identify #Xkr8 #phospholipid #scramblase as responsible for #phosphatidylserine eat-me signal exposure and #axon pruning to prevent global hyperconnectivity
https://www.embopress.org/doi/10.15252/embj.2022111790
The EMBO JournalDec 15, 2022

#CryoEM #structures of #ABCA7 #exporter in different states reveal a bellows-like model for #phospholipid extrusion from #membranes

New #article by Amer Alam and colleagues, The Hormel Institute

https://www.embopress.org/doi/10.15252/embj.2022111065

The EMBO JournalDec 1, 2022

Featured in issue 23 of our anniversary year:
How delayed folding aids #protein secretion

Plant and mammalian #ubiquitin E3 #ligases against #bacterial #infection
#CryoEM glimpses at membrane pore formation and #ion transporters
#Autophagosomes in need of balanced #phospholipid composition
#Hypoxia promotes #osteogenesis by facilitating #mitochondria to
#nucleus communication

Cover by by Subhash Mehto, Kautilya Kumar Jena, Santosh Chauhan et al
https://www.embopress.org/toc/14602075/2022/41/23