Researchers identified a rare #genetic mutation, C182F, within the TAAR1 #brain receptor that completely negates the efficacy of newer #schizophrenia treatments by structurally locking the receptor in an inactive state.
#Psychiatry #Pharmaceutical #Pharmacogenomics #MolecularPsychiatry #sflorg
https://www.sflorg.com/2026/02/psyc02042601.html
Tiny mutation, big impact on schizophrenia treatment

Schizophrenia affects about 23 million people worldwide and is one of the hardest mental health conditions to manage

💊 Think your prescription changes are random? Your genes might be calling the shots.

🔗 Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.042

📚 CSBJ Smart Hospital: https://www.csbj.org/smarthospital

#Genomics #Polypharmacy #PersonalizedMedicine #Pharmacogenomics #DrugSafety #GWAS #PrecisionMedicine #Pharmacology #Genetics #MedTech

Cytochrome P450: The Key to Drug Metabolism and Mental Health - Rackenzik

Cytochrome P450 regulates drug metabolism, shaping psychiatric treatment with precision medicine and genetic insights for better care.

Rackenzik

In July 2024, we conducted a survey on behalf of Queen Mary University London (QMUL), using our probability-based NatCen Opinion Panel, to explore public #Attitudes towards genetic testing to predict medicine response, known as #Pharmacogenomics.

🔗 Read the full report:

https://natcen.ac.uk/publications/attitudes-towards-genetic-testing-predict-medicine-response

#Pharmacogenomics #PublicHealth #HealthCare #Surveys

Attitudes towards genetic testing to predict medicine response | National Centre for Social Research

A nationally representative survey on public attitudes towards genetic testing to understand and personalise medicine response.

National Centre for Social Research

The book that I edited and co-authored is finally published! It's a compilation of scientific writings on the recent advances in #genomics and #pharmacogenomics . Thus, thanks also to fellow editors & authors for their hard work for finishing the book. if you are interested in our works, please check on this link below: 👇

https://www.igi-global.com/book/genomics-driven-drug-discovery-through/344805

#i3L #biotechnology #biomedicine #bioinformatics #GIAR

Environmental Factors in the Pathogenesis of Cardiovascular Diseases

This book provides comprehensive and up-to-date information from top-notch investigators in the field on this non-communicable disease

SpringerLink
📢 Announcing the #Pharmacogenomics Track - OAEI #Ontology Matching @iswc_conf
#ISWC2024 w/ Adrien Coulet
Structure-based instance matching with multiple alignment types (sameAs, broadMatch, etc)
Feel free to contact me for any questions!
📎http://oaei.ontologymatching.org/2024/pharmacogenomics/index.html
#knowledgeGraph #semanticWeb #linkedOpenData
Ontology Alignment Evaluation Initiative::Pharmacogenomics Track

VIPs: Very Important Pharmacogenes
https://www.pharmgkb.org/vips

"The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including clinical guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships."
https://www.pharmgkb.org/about

#pharmacogenomics #pharmacogenetics #pharmacy #pharmacology #genetics #genomics #DrugMetabolism
#medicine

PharmGKB

PharmGKB