Dynamic BH3 profiling (DBP) is an advanced functional assay that predicts the efficacy of specific cancer treatments by testing them directly on living tumor cells.
#MolecularOncology #PrecisionMedicine #CellBiology #Pharmacogenomics #sflorg
https://www.sflorg.com/2026/06/ongy06032601.html
Dynamic BH3 Profiling in Lung Cancer

Discover how Dynamic BH3 profiling tests targeted therapies directly on living cells to predict treatment success for non-small cell lung cancer.

Researchers identified a rare #genetic mutation, C182F, within the TAAR1 #brain receptor that completely negates the efficacy of newer #schizophrenia treatments by structurally locking the receptor in an inactive state.
#Psychiatry #Pharmaceutical #Pharmacogenomics #MolecularPsychiatry #sflorg
https://www.sflorg.com/2026/02/psyc02042601.html
Tiny mutation, big impact on schizophrenia treatment

Schizophrenia affects about 23 million people worldwide and is one of the hardest mental health conditions to manage

πŸ’Š Think your prescription changes are random? Your genes might be calling the shots.

πŸ”— Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.042

πŸ“š CSBJ Smart Hospital: https://www.csbj.org/smarthospital

#Genomics #Polypharmacy #PersonalizedMedicine #Pharmacogenomics #DrugSafety #GWAS #PrecisionMedicine #Pharmacology #Genetics #MedTech

Cytochrome P450: The Key to Drug Metabolism and Mental Health - Rackenzik

Cytochrome P450 regulates drug metabolism, shaping psychiatric treatment with precision medicine and genetic insights for better care.

Rackenzik

In July 2024, we conducted a survey on behalf of Queen Mary University London (QMUL), using our probability-based NatCen Opinion Panel, to explore public #Attitudes towards genetic testing to predict medicine response, known as #Pharmacogenomics.

πŸ”— Read the full report:

https://natcen.ac.uk/publications/attitudes-towards-genetic-testing-predict-medicine-response

#Pharmacogenomics #PublicHealth #HealthCare #Surveys

Attitudes towards genetic testing to predict medicine response | National Centre for Social Research

A nationally representative survey on public attitudes towards genetic testing to understand and personalise medicine response.

National Centre for Social Research

The book that I edited and co-authored is finally published! It's a compilation of scientific writings on the recent advances in #genomics and #pharmacogenomics . Thus, thanks also to fellow editors & authors for their hard work for finishing the book. if you are interested in our works, please check on this link below: πŸ‘‡

https://www.igi-global.com/book/genomics-driven-drug-discovery-through/344805

#i3L #biotechnology #biomedicine #bioinformatics #GIAR

Environmental Factors in the Pathogenesis of Cardiovascular Diseases

This book provides comprehensive and up-to-date information from top-notch investigators in the field on this non-communicable disease

SpringerLink
πŸ“’ Announcing the #Pharmacogenomics Track - OAEI #Ontology Matching @iswc_conf
#ISWC2024 w/ Adrien Coulet
Structure-based instance matching with multiple alignment types (sameAs, broadMatch, etc)
Feel free to contact me for any questions!
πŸ“Žhttp://oaei.ontologymatching.org/2024/pharmacogenomics/index.html
#knowledgeGraph #semanticWeb #linkedOpenData
Ontology Alignment Evaluation Initiative::Pharmacogenomics Track

VIPs: Very Important Pharmacogenes
https://www.pharmgkb.org/vips

"The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including clinical guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships."
https://www.pharmgkb.org/about

#pharmacogenomics #pharmacogenetics #pharmacy #pharmacology #genetics #genomics #DrugMetabolism
#medicine

PharmGKB

PharmGKB