#Italy, #traveler from #DRC tested negative after molecular diagnostics performed, https://www.iltirreno.it/lucca/cronaca/2024/12/20/news/lucca-test-negativi-sul-paziente-rientrato-dal-congo-1.100635824

Patient was negative for #Alphavirus, #Flavivirus, #RVF, #Lassa, #influenza A, influenza B, #SARS-CoV-2, #rhinovirus, NL63, 229E, OC43 e HKU1, PIV 1, 2, 3 e 4, #metapneumovirus A/B, #bocavirus, #RSV A/B, #adenovirus, #parechovirus, Borrelia spp, Borrelia recurrentis, Borrelia duttoni, Borrelia TBRF group, Bartonella spp, Erlichia spp, Rickettsia spp, virus del morbillo, Plasmodium spp.

Characterising molecular #epidemiology of #human #parechovirus in young #infants in #UK and #Canada, J Clin Virol.: https://www.sciencedirect.com/science/article/pii/S1386653224000775?dgcid=rss_sd_all

Most human parechovirus (#HPeV) infections detected in infants were genotype 3 (HPeV-A3; 57/58 cases). A genotype 5 strain (HPeV-A5) was detected for the first time in U.K. Strains of HPeV-A3 from UK and Canada were phylogenetically interspersed. No association was seen between #severity of disease and HPeV phylogenetic grouping.

#Parechovirus #infection in #human #brain #organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease https://www.nature.com/articles/s41467-024-46634-9

In comparison to PeV-A1, infection with PeV-A3 is associated with neurological illness in infants. Here, using brain organoids, the authors suggest that the innate inflammatory response as the underlying reason, and not replication kinetics.