Issue 14:
Highlight on #ROR1 and #pancreatic #malignancy

Review on viral recognition and #antiviral #interferon response

#Autophagy news from plants and mammals
How #p97 disassembles a regulatory protein complex
Developmental #axon pruning by a #phospholipid #scramblase

Cover: Elisa Nerli, Caren Norden and colleagues

https://www.embopress.org/toc/14602075/2023/42/14

How does p97/VCP #ATPase achieve selective disassembly of regulatory protein complexes? #CryoEM showing #p97 holding on to one #PP1 partner, while threading another, suggest a hold-and-extract mechanism
Hemmo Meier, Helen Saibil and coworkers
https://www.embopress.org/doi/10.15252/embj.2022113110

The latest results from my postdoc at the Kulathu lab are now on BioRxiv!
🔗 http://bit.ly/branched-K48-K63-Ub 🔗

#ubiquitin #nanobody #DUBs #p97

Amazing team effort - thanks to everyone involved!🥳