A fentanyl vaccine is about to get its first major test https://arstechni.ca/yTqr #syndication #fentanyl #vaccines #Science #opioids #Health
A fentanyl vaccine is about to get its first major test

Vaccine trial in the Netherlands hopes to protect against fentanyl-related overdose and death.

Ars Technica

"ARMR’s experimental vaccine is designed to neutralize fentanyl in the bloodstream before it reaches the brain. Keeping fentanyl out of the brain would prevent the respiratory failure that comes with overdose, which causes death, as well as the euphoric high people get while taking fentanyl.

The basic idea behind ARMR’s shot is the same as any other vaccine. It trains the body’s immune system to make antibodies that recognize a foreign invader. But since fentanyl is much smaller than the pathogens our current vaccines target, it doesn’t trigger a natural antibody response on its own. To stimulate antibody production, ARMR has paired a fentanyl-like molecule with a “carrier” protein—a deactivated diphtheria toxin that’s already used in several approved medical products.

If a vaccinated person encounters fentanyl, antibodies in the blood would then bind to the drug and prevent it from traveling to the brain. Normally, fentanyl molecules can pass through the blood-brain barrier with ease, in part because of their small size. But fentanyl molecules with antibodies attached would be too big to get through." #fentanyl #opioids #vaccines https://www.wired.com/story/a-fentanyl-vaccine-is-about-to-get-its-first-major-test/

A Fentanyl Vaccine Is About to Get Its First Major Test

ARMR Sciences of New York is trialing a vaccine in the Netherlands to protect against fentanyl-related overdose and death.

WIRED

The opening of a new day detox program offered by the Royal Ottawa Mental Health Centre will help more people get treatment for alcohol and opioid use, and should make a huge difference to their lives.

https://ottawacitizen.com/news/royal-day-detox-beds

#Ottawa #Canada #Health #opioids #stigma #TalkOverdose #ParlonsSurdose

Royal opens 'day detox' beds to enhance addictions treatment

The initiative is aimed at helping more people receive addictions treatment.

ottawacitizen

Opioids: Last Week Tonight with John Oliver (HBO)

https://peertube.gravitywell.xyz/w/bNNRhbAE6fYPfQp8izAjnw

Opioids: Last Week Tonight with John Oliver (HBO)

PeerTube

Sen. Imee Marcos raises drug claim against Philippine leader in family spat

MANILA, Philippines (AP) — Philippine President Ferdinand Marcos Jr.’s estranged sister, a senator, publicly accused him Monday of…
#NewsBeep #News #Headlines #Bribery #ClaireCastro #Corruption #FerdinandMarcosJr. #Generalnews #InternationalNews #LizaMarcos #Manila #Opioids #Painmanagement #Philippines #Politics #RodrigoDuterte #SandroMarcos #SaraDuterte #Scandals #World #Worldnews
https://www.newsbeep.com/257176/

‘The Next Wave in the Opioid Crisis’: A New Drug Stronger Than Fentanyl Is Taking Off

https://fed.brid.gy/r/https://www.rollingstone.com/culture/culture-features/nitazene-opioid-fentanyl-crisis-1235465350/

US bankruptcy court to approve deal with Purdue Pharma and Sackler family | Drugs News | Al Jazeera
#Opioids #Addiction

https://www.aljazeera.com/news/2025/11/15/us-bankruptcy-court-to-approve-deal-with-purdue-pharma-and-sackler-family

US bankruptcy court to approve deal with Purdue Pharma and Sackler family

The deal is expected to be one of the largest settlements against an opioid manufacturer, with funds for victims.

Al Jazeera

The deal is among the largest in a series of opioid settlements brought by state & local governments against drugmakers, wholesalers & pharmacies that totaled about $50 billion. It could close a long chapter — & maybe the entire book — on a legal odyssey over efforts to hold the company to account for its role in an #OpioidCrisis connected to 900,000 deaths in the U.S. since 1999, including deaths from #heroin & illicit #fentanyl.

#law #Sackler #PurduePharma #BigPharma #opioids