Moritz NegwerSep 9, 2024

New #tissueclearing paper checks oligodendrocyte distribution throughout the entire mouse brain. Looks pretty neat!

Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan
Xu et al., preprint at biorxiv 2024
https://doi.org/10.1101/2024.09.06.611254

Github: https://github.com/yxu233/Xu_Bergles_brainwide_oligo_map

#neuroscience #lightsheet #microscopy #preprint #oligodendrocyte #myelination

PLOS BiologyJul 12, 2024
The diversity of #oligodendrocyte precursor cells (OPCs) is unclear. @Czopka_Lab explores a #PLOSBiology study describing a novel marker for a subpopulation of #OPCs that controls #oligodendrogenesis & #myelination. Paper: https://plos.io/3xS0sKE Primer: https://plos.io/3xTyrCx
A molecularly defined subpopulation of oligodendrocyte precursor cells controls the generation of myelinating oligodendrocytes during postnatal development

Oligodendrocyte precursor cells are a diverse population; does this functional diversity arise from the existence of molecularly defined subpopulations or from environmental interactions? This study shows that C1ql1 expression defines a subpopulation of oligodendrocyte precursor cells that are indispensable for production of oligodendrocytes and myelin during postnatal brain development.

PLOS BiologyJul 11, 2024
How does #oligodendrocyte precursor cell (OPC) diversity arise? @fekrijeselimi &co show that C1ql1 expression defines an #OPC subpopulation that sis essential for production of oligodendrocytes & #myelin during postnatal brain development #PLOSBiology https://plos.io/3xS0sKE
A molecularly defined subpopulation of oligodendrocyte precursor cells controls the generation of myelinating oligodendrocytes during postnatal development

Oligodendrocyte precursor cells are a diverse population; does this functional diversity arise from the existence of molecularly defined subpopulations or from environmental interactions? This study shows that C1ql1 expression defines a subpopulation of oligodendrocyte precursor cells that are indispensable for production of oligodendrocytes and myelin during postnatal brain development.

Scientific FrontlineApr 17, 2023
Researchers at UC Davis are the first to report how a specific type of #brain #cells, known as #oligodendrocyte-lineage cells, transfer cell material to #neurons in the mouse brain. Opens treatment possibilities for #Alzheimer’s, #Parkinson’s and #Huntington’s diseases
#Neuroscience #Biology #sflorg
https://www.sflorg.com/2023/04/ns04172301.html
Researchers discover how some brain cells transfer material to neurons in mice

New study opens treatment possibilities for Alzheimer’s, Parkinson’s and Huntington’s diseases

AchucarroDec 6, 2022
Technical approaches and challenges to study #AMPA receptors in #oligodendrocyte lineage cells #glia
https://doi.org/10.1002/glia.24305
ipekselcenNov 6, 2022
#introduction Hi everyone!
I’m Ipek and I work on the regulation of distinct #TET isoforms in adult #oligodendrocyte progenitor cells.
I have a master’s in molecular biology and genetics from Bogazici University and I’m a PhD candidate in biochemistry/neuroscience at CUNY ASRC.