New publication: Two deeply conserved non-coding sequences control PLETHORA1/2 expression and coordinate embryo and #root development. #geneexpression #noncodingDNA
https://doi.org/10.1016/j.xplc.2025.101466

The mutational landscape and functional effects of noncoding ultraconserved elements in human cancers
https://www.science.org/doi/10.1126/sciadv.ado2830
pdf: https://www.science.org/doi/epdf/10.1126/sciadv.ado2830

* diverse regulatory roles in cancer

#cancer #genetics #genomics #FunctionalGenomics #NoncodingDNA #ncDNA #miRNA #GeneRegulation #CRISPR

Scots scientists uncover DNA 'switch' which affects anxiety levels

The team found a section of DNA that 'switches' on key genes in parts of the brain that affect anxiety levels in mice.

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