New #NeuroPaper, looks very interesting!
”Our study is a call for academics to clarify what they mean by ‘behavior’ wherever they study it, with the hope that this will foster interdisciplinary studies that will improve our understanding of behavioral phenomena.”
Everyone knows what behavior is but they just don’t agree on it
Another really cool #NeuroPaper, this one about rule-switching:
Sharp-wave-ripple-associated activity in the medial prefrontal cortex supports spatial rule switching
#KloostermanLab #mPFC #Hippocampus #SWR #NeuroRats #Optogenetics
Potentially very interesting #NeuroPaper in #Humans:
Backbone spiking sequence as a basis for preplay, replay, and default states in human cortex
(Thanks to my colleague Hung-Tu for highlighting this one!)
(I’m not sure we can really say that preplay has been “robustly demonstrated” in rodents though…)
#Replay #Preplay #AnteriorTemporalLobe #MicroElectrodeArray #NeuroHuman
Sequential neural spiking activity is a potential substrate for learning and memory across species. Here, the authors showed spiking in the human cortex forms an average backbone sequence, and flexibility around this backbone is associated with cognition.
I am pleased to link here the second paper in our series investigating the connectivity between the ventral premotor cortex and the primary motor cortex by means of transcranial magnetic stimulation.
"The ventral premotor cortex (PMv) and primary motor cortex (M1) represent critical nodes of a parietofrontal network involved in grasping actions, such as power and precision grip. Here, we investigated how the functional PMv-M1 connectivity drives the dissociation between these two actions. We applied a PMv-M1 cortico-cortical paired associative stimulation (cc-PAS) protocol, stimulating M1 in both postero-anterior (PA) and antero-posterior (AP) directions, in order to induce long-term changes in the activity of different neuronal populations within M1. We evaluated the motor-evoked potential (MEP) amplitude, MEP latency and cortical silent period, in both PA and AP, during the isometric execution of precision and power grip, before and after the PMv-M1 cc-PAS. The repeated activation of the PMv-M1 cortico-cortical network with PA orientation over M1 did not change MEP amplitude or cortical silent period duration during both actions. In contrast, the PMv-M1 cc-PAS stimulation of M1 with an AP direction led to a specific modulation of precision grip motor drive. In particular, MEPs tested with AP stimulation showed a selective increase of corticospinal excitability during precision grip. These findings suggest that the more superficial M1 neuronal populations recruited by the PMv input are involved preferentially in the execution of precision grip actions."
Here is the link:
https://pubmed.ncbi.nlm.nih.gov/37526070/
Previous paper:
https://pubmed.ncbi.nlm.nih.gov/36327142/
The ventral premotor cortex (PMv) and primary motor cortex (M1) represent critical nodes of a parietofrontal network involved in grasping actions, such as power and precision grip. Here, we investigated how the functional PMv-M1 connectivity drives the dissociation between these two actions. We appl …
A key idea behind the brain's ability to #flexibly and #rapidly #compute is its #shortterm #plasticity ! The mechanism was beautifully reviewed by the late Mark Stokes:
‘Activity-silent’ working memory in prefrontal cortex: a dynamic coding framework
https://www.cell.com/fulltext/S1364-6613(15)00102-3
Seeing ideas like these included in modern #ML models more and more now - extremely exciting to see how this will work out in #technology !
Super thoughtful #neuroscience paper reconciling findings from work on #memory by factoring in generalisation abilities:
Organizing memories for generalization in complementary learning systems
by Weinan Sun, Madhu Advani, Nelson Spruston, Andrew Saxe & James E. Fitzgerald
https://www.nature.com/articles/s41593-023-01382-9
#newpaper #neuro #neuropaper #ML #neuralnetwork #learning @neuroscience
The authors derive a neural network theory of systems consolidation to assess why some memories consolidate more than others. They propose that brains regulate consolidation to optimize generalization, so only predictable memory components consolidate.
(Hi all... pardon me for this mass-tagging...)
@WorldImagining yes!
@hugospiers:
For hashtags, also try out #Navigation #NeuroPreprint #NeuroPaper ... and some non-neuro (broken to not contaminate them): # Bloomscrolling # Mosstodon # Caturday # Raturday # SciArt
Here are some great accounts that I follow, and that should be active (in no specific order), you'll probably recognize most of them:
@NicoleCRust
@PhiloNeuroScie
@achterbrain
@karihoffman
@katejjeffery
@paulgribble
@AllenNeuroLab
@Neurograce
@nadel
@markgbaxter
@albertcardona
@chrisXrodgers
@adredish
@dlevenstein
@vineettiruvadi
@GunnarBlohm
@jpeelle
@manisha
@DrYohanJohn
@alicia_izquierdo
@susanleemburg
@guidomeijer
@computingnature
@Andrewpapale
@MatteoCarandini
@UCL_NeuroAI
@ArminLak
@meganakpeters
@kordinglab
@neuralreckoning
@obarnstedt
@marcwhoward
@socneuronerd
@kevinbolding
@olivia
@PessoaBrain
@BenoitGirard
@ [email protected]
@ [email protected]
@ [email protected]
and the best one:
@ [email protected]
https://fediscience.org/public/local
https://synapse.cafe/public/local
https://scicomm.xyz/public/local
(unfortunately our instance neuromatch.social does not have an open local timeline for now)
@jonny
@lisamelton
@alexwild
@inthehands
@liztai
@schoppik
@rodhilton
@Mrfunkedude
@emmatonkin
@rolle
@breadandcircuses
@tchambers
@theLastTheorist
@Em0nM4stodon (special mention to the great tips on her profile 👍)
@futurebird
@ct_bergstrom
@alexwild
@artologica
@OkieSpaceQueen
@mariyadelano
@juliancday
I could add more but I would spend the night on it! I've only reached page 5 /27 of my 'follows and followers' tab (and this is a selection)
Hope this helps! Please don't hesitate to ask anything :)
(Edit: formatting)
El Duvelle Neuro
El Duvelle
Alessandro D'Ausilio
Jascha Achterberg