Mastodawn

🧠 What can a single neuron compute?

A new #bioRxiv #preprint introduces #TwinProp, using a differentiable digital twin to optimize synaptic strengths and locations in a detailed layer 5 #pyramidal #CellModel. One #neuron classified images and speech and even solved 10-bit parity with 91% accuracy. The key: distributed #dendritic nonlinearities, especially #NMDA-dependent integration:

📄 https://doi.org/10.64898/2026.06.08.730984

#CompNeuro #Neuroscience #Dendrites #NeuroAI @albertcardona https://mathstodon.xyz/@albertcardona/116764629463190653

The vOICe vision BCI 🧠🇪🇺Jun 16

Discovering functionally selective brain regions with a deep topographic multimodal model https://arxiv.org/abs/2606.09770 #AI #NeuroAI #neuroscience

Discovering Functionally Selective Brain Regions with a Deep Topographic Multimodal Model

Nearby neurons in cortex share similar response profiles, producing systematic spatial organization across sensory and cognitive systems. Recent topographic models reproduce aspects of this structure but remain unimodal and spatially constrain each layer separately, yielding fragmented maps that capture neither the contiguity of cortical processing streams nor their integration across modalities. We introduce Topo-Omni, a topographic multimodal model in which visual, auditory, and language/cognitive processing share a single contiguous in-silico sheet. Built by fine-tuning a pretrained foundation model with a spatial smoothness objective, this architecture develops clusters across modalities that are consistent with human neuroimaging, from sensory to cognitive systems. Driving or suppressing a cluster selectively biases or impairs perception, paralleling human intervention studies. Finally, we use our model to screen for novel clusters in-silico and discover new natural landscape and animal networks which we validate in human data. A single spatial principle thus organizes representations across modalities and processing stages, yielding testable hypotheses about cortical organization.

arXiv.org

The vOICe vision BCI 🧠🇪🇺Jun 16

Might such a multimodal AI model yield novel insights in mastering visual-to-auditory sensory substitution through cortical map formation? www.youtube.com/watch?v=nVug... #AI #NeuroAI #neuroscience

RE: https://bsky.app/profile/did:plc:k2dsj35dupolhkgkmyharjhz/post/3mofry2gck22t

Neuralink Blindsight or The vO...

Tim Green Jun 11

Advances in mechanistic interpretability are revealing how large language models organise concepts internally, mimicking human brains. These insights could underpin safer, more transparent AI deployment in high-stakes scenarios.
Discover more at https://dev.to/rawveg/reading-machine-minds-5ace
#HumanInTheLoop #AIinterpretability #NeuroAI #AISafety

Reading Machine Minds

Somewhere inside Claude, Anthropic's large language model, there is a cluster of artificial neurons...

DEV Community

The vOICe vision BCI 🧠🇪🇺Jun 5

EPFL claims: AI brings object-level vision prosthetics closer to reality https://actu.epfl.ch/news/ai-brings-object-level-vision-prosthetics-closer-t/

"EPFL researchers are developing AI models that could one day enable vision prosthetics able to restore meaningful, object-level sight for the blind."

Using "AI models to predict exactly where to stimulate the brain to evoke images of faces and specific objects in the users instead of simply evoking spots of light."

Underlying scientific paper (2025): Model-guided microstimulation steers primate visual behavior https://arxiv.org/abs/2510.03684

#AI #NeuroAI #BCI #blindness

The vOICe vision BCI 🧠🇪🇺Jun 5

#AI brings object-level vision prosthetics closer to reality techxplore.com/news/2026-06... using "AI models to predict exactly where to stimulate the brain to evoke images of faces and specific objects in the users instead of simply evoking spots of light"; #NeuroAI #BCI #blindness

RE: https://bsky.app/profile/did:plc:ohkmmhqij4kit43lccgdx7gx/post/3m2okmhjlos2o

AI brings object-level vision ...

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The vOICe vision BCI 🧠🇪🇺Jun 1

It will be a challenge for #NeuroAI researchers to train #AI models and realize closed-loop noninvasive brain stimulation that performs this effective nudging towards desired (e.g. healthier) brain states.

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The vOICe vision BCI 🧠🇪🇺Jun 1

The vOICe vision BCI 🧠🇪🇺May 28

(YouTube) Jacques Carolan — The mission to get breakthrough brain treatments to everyone https://www.youtube.com/watch?v=RAmigpsKCQY on #neuromodulation #NeuroTech #NeuroAI #neuroscience