An intriguing twist! TDP-43 (linked to #ALS) keeps RNAs out of neuronal projections by making them unstable, preventing RNA buildup in neurites. #preprint from the #TaliaferroLab
Another excellent post prepared by Felipe Del Valle Batalla π
#preLight β¬οΈ π
https://prelights.biologists.com/highlights/tdp-43-directly-inhibits-rna-accumulation-in-neurites-through-modulation-of-rna-stability/