Bad sleep made woman's eyelids so floppy they flipped inside out, got stuck https://arstechni.ca/KAR9 #obstructivesleepapnea #floppyeyelidsyndrome #eyelids #Health #sleep #NEJM #eye
Bad sleep made woman's eyelids so floppy they flipped inside out, got stuck

Never underestimate the value of a good night's sleep.

Ars Technica

Finally, my warmest thanks to the CRICS-TriggerSep Scientific Board for their crucial role in designing and conducting this trial.

https://www.nejm.org/doi/full/10.1056/NEJMoa2502136

#EVERDAC #CriticalCare #ESICM2025 #NEJM #ICU #Research #CRICSTriggerSep

Deferring Arterial Catheterization in Critically Ill Patients with Shock | NEJM

In patients with shock, whether noninvasive blood-pressure monitoring is an effective alternative to the recommended use of an arterial catheter is uncertain. In this multicenter, open-label, nonin...

The New England Journal of Medicine
Apixaban for Extended Treatment of Provoked Venous Thromboembolism. #NEJM "Low-intensity therapy with apixaban for 12 months resulted in a lower risk of symptomatic recurrent VTE than placebo, with a low risk of major bleeding." www.nejm.org/doi/full/10....
Medical Imaging and Pediatric and Adolescent Hematologic Cancer Risk. #nejm "Our study suggests an association between exposure to radiation from medical imaging and a small but significantly increased risk of hematologic cancer among children and adolescents." www.nejm.org/doi/full/10....

Medical Imaging and Pediatric ...
In adults with obesity, 72-week treatment with orforglipron led to significantly greater reductions in body weight than placebo; the adverse-event profile was consistent with that of other GLP-1 receptor agonists. #NEJM www.nejm.org/doi/full/10....

Orforglipron, an Oral Small-Mo...
Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment | NEJM

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity. In this phase 3, multinational, randomized, doubl...

The New England Journal of Medicine
Marburg Virus Disease in Rwanda, 2024 — Public Health and Clinical Responses. #NEJM Open Access www.nejm.org/doi/full/10....
In resectable lung cancer, neoadjuvant nivolumab plus chemotherapy improved 5-year overall survival, with no lung cancer deaths reported at 5 years in patients with a pathological complete response. #NEJM www.nejm.org/doi/full/10....

Update. Three past editors of the New England Journal of Medicine (#NEJM) answer the attack on their journal from #RFKJr.
https://www.statnews.com/2025/06/30/rfk-jr-medical-journals-nejm-jama-lancet-editors-respond-medical-journals-ethics/
(#paywalled)

"Kennedy claimed that one of us (Angell) said, 'We are no longer a science journal, we are a vessel for pharmaceutical propaganda.' In fact, what Angell said in a 2009 article was that 'it is simply no longer possible to believe much of the clinical research that is published,' due to researchers’ financial ties with pharmaceutical companies."

The editors also point out that the three journals named by Kennedy happen to have published editorials criticizing the #Trump admin assault of science.

#DefendResearch #Medicine #Pharma #ScholComm #TrumpVResearch #USPol #USPolitics

RFK Jr. says medical journals are ‘corrupt.’ As former NEJM editors, we know he’s wrong

RFK Jr.’s plan to circumvent established medical journals smacks more of retaliation than reform, write three former NEJM editors.

STAT
Man fails to take his medicine—the flesh starts rotting off his leg https://arstechni.ca/2pVY #bloodpressure #casestudy #medicine #Health #Ulcer #NEJM
Man’s ghastly festering ulcer stumps doctors—until they cut out a wedge of flesh

The man made a full recovery, but this tale is not for the faint of heart.

Ars Technica