Scientific Frontline3d ago
A novel stem cell therapy that integrates biodegradable #nanogel microfibers into three-dimensional cell clusters (#spheroids ) to enhance stem cell survival, oxygen diffusion, and functional regeneration of injured swallowing muscles.
#Bioengineering #MaterialScience #CellBiology #sflorg
https://www.sflorg.com/2026/03/beng03142601.html
Giving stem cells room to breathe

Stem cell therapy is considered a promising strategy for muscle repair

Howard Smith MD, AMMar 18, 2025
Nano-eradication of Recurrent Bladder Infections: Nanogel+penetrating agent+antibiotic kill bacteria that hide within bladder lining cells and perpetuate urinary tract infections. #cystitis #bladder #infection #itaconate #nanogel #gentamycin
https://www.instagram.com/reel/DHWrZMmM_b_/
Howard G. Smith MD, AM on Instagram: "Nano-eradication of Recurrent Bladder Infections A nanogel coupled with a cell-penetrating compound more effectively delivers antibiotics to kill bacteria that hide within bladder lining cells and perpetuate urinary tract infections. Pharmacologists and microbiologists from the University of Colorado’s Anschutz Campus report the successful development and deployment of just such a drug. The researchers combined polymeric nanogels with a peptide compound that eases their cellular entry and the antibiotic gentamicin in order to effectively kill pseudomonas bacteria that hide within bladder lining cells. When injected into the bladder, this nanogel-peptide-antibiotic complex is able to convey 36% more of the antibiotic into the cell interior than conventional administration techniques. When tested in animal models, it successfully eliminates more than 90% of bladder bacteria. This technique shows great promise for more effective management of not only persistent and recurrrent bladder infections but also tenacious infections elsewhere in the urinary tract and other organs. https://www.sciencedirect.com/science/article/abs/pii/S1549963425000127?via=ihub https://www.sciencedaily.com/releases/2025/03/250312124140.htm#google_vignette #cystitis #bladder #infection #itaconate #nanogel #gentamycin"

0 likes, 0 comments - drhowardsmithreports on March 18, 2025: "Nano-eradication of Recurrent Bladder Infections A nanogel coupled with a cell-penetrating compound more effectively delivers antibiotics to kill bacteria that hide within bladder lining cells and perpetuate urinary tract infections. Pharmacologists and microbiologists from the University of Colorado’s Anschutz Campus report the successful development and deployment of just such a drug. The researchers combined polymeric nanogels with a peptide compound that eases their cellular entry and the antibiotic gentamicin in order to effectively kill pseudomonas bacteria that hide within bladder lining cells. When injected into the bladder, this nanogel-peptide-antibiotic complex is able to convey 36% more of the antibiotic into the cell interior than conventional administration techniques. When tested in animal models, it successfully eliminates more than 90% of bladder bacteria. This technique shows great promise for more effective management of not only persistent and recurrrent bladder infections but also tenacious infections elsewhere in the urinary tract and other organs. https://www.sciencedirect.com/science/article/abs/pii/S1549963425000127?via=ihub https://www.sciencedaily.com/releases/2025/03/250312124140.htm#google_vignette #cystitis #bladder #infection #itaconate #nanogel #gentamycin".

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ChemistryViewsJan 20, 2025

Polyglycerol Nanogels for Periodontitis Treatment:
Dual-function nanogel combines antimicrobial and pro-angiogenesis medications to combat microbes and promote tissue regeneration
https://www.chemistryviews.org/polyglycerol-nanogels-for-periodontitis-treatment/

#periodontitis #nanogel #drugdelivery #chemistry #chemistryviews #chemviews

Polyglycerol Nanogels for Periodontitis Treatment - ChemistryViews

Dual-function nanogel combines antimicrobial and pro-angiogenesis medications to combat microbes and promote tissue regeneration

ChemistryViews
Poetry NewsSep 8, 2023

Drug to liver carries
Synthetic hormone to treatment
Cholesterol reduced

#nanogel #thyroid #cholesterol #obesity #haiku #poetry

http://www.medicalnewstoday.com/articles/synthetic-thyroid-hormone-may-lower-cholesterol-treat-obesity

Synthetic thyroid hormone may lower cholesterol, treat obesity

A nanogel-based carrier delivering a thyroid hormone-mimicking drug directly to the liver successfully lowered cholesterol levels and reversed obesity in mice.

Medical News Today
Futuro Prossimo Sep 6, 2023

I ricercatori dell'Università del Massachussetts Amherst hanno sviluppato un metodo rivoluzionario per somministrare farmaci anticolesterolo direttamente al fegato attraverso un vettore nanogel. I risultati dei test sui topi? Sorprendenti: inversione delle condizioni di malattia e abbattimento dell'obesità anche in presenza di una dieta ad alto contenuto di grassi. Il prossimo passo, dagli esiti non scontati, è quello dei test sull'uomo.

#Colesterolo #Nanogel #Obesità

https://www.futuroprossimo.it/2023/09/nuovo-farmaco-anticolesterolo-abbatte-anche-obesita-nei-test-sui-topi/

Nuovo farmaco anticolesterolo abbatte anche obesità nei test sui topi

Risultati sorprendenti dai test di un farmaco anticolesterolo a base di nanogel: obesità eliminata anche in presenza di alimentazione grassa

Futuro Prossimo