U01.17.045 Botulism: Clostridium botulinum Toxin and Flaccid Paralysis

Master Botulism (U01.17.045) for USMLE Step 1. Learn about Botulinum toxin, SNARE protein cleavage, and the "4 D's" of clinical presentation. High-yield guide on mymedschool.org.

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U01.17.044 Tetanus: Clostridium tetani Pathophysiology and Spastic Paralysis

Master Tetanus (U01.17.044) for USMLE Step 1. Learn about Tetanospasmin, retrograde axonal transport, and the mechanism of GABA/Glycine inhibition. High-yield guide on mymedschool.org.

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U01.17.043 Hemolytic-Uremic Syndrome (HUS): Triad, Toxins, and Treatment

Master Hemolytic-Uremic Syndrome (U01.17.043) for USMLE Step 1. Learn about Shiga-like toxin, EHEC O157:H7, the clinical triad of anemia, thrombocytopenia, and renal failure, and why antibiotics are contraindicated. High-yield guide on mymedschool.org.

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U01.17.011 Duchenne Muscular Dystrophy (DMD): Genetics and Clinical Hallmarks

Master Duchenne Muscular Dystrophy (U01.17.011) for USMLE Step 1. Learn about dystrophin frameshift mutations, Gowers sign, and the causes of pseudohypertrophy. High-yield guide on mymedschool.org.

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U01.17.010 Cystic Fibrosis: CFTR Mutations, Diagnosis, and Management

Master Cystic Fibrosis (U01.17.010) for USMLE Step 1. Learn about the ΔF508 mutation, CFTR chloride channel defects, sweat chloride testing, and multisystem complications. High-yield guide on mymedschool.org.

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Master Angelman Syndrome (U01.17.009) for USMLE Step 1. Learn about Chromosome 15 imprinting, Maternal deletion of the UBE3A gene, and characteristic clinical features. High-yield guide on mymedschool.org.

U01.17.009 Summary: Understand the genetic "silencing" of the paternal chromosome. Explore why the loss of the maternal UBE3A allele results in ataxia, seizures, and a frequent smiling/laughter phenotype.

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U01.17.008 Prader–Willi Syndrome: Imprinting Defects and Hyperphagia

Master Prader–Willi Syndrome (U01.17.008) for USMLE Step 1. Learn about Chromosome 15 imprinting, Paternal deletion, and the clinical presentation of neonatal hypotonia and obesity. High-yield guide on mymedschool.org.

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U01.17.007 Marfan Syndrome: Fibrillin-1 Mutations and Clinical Triad

Master Marfan Syndrome (U01.17.007) for USMLE Step 1. Learn about FBN1 gene mutations, TGF-ß signaling, and life-threatening cardiovascular complications like Aortic Dissection. High-yield guide on mymedschool.org.

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U01.17.006 Menkes Disease: Copper Transport and Kinky Hair Syndrome

Master Menkes Disease (U01.17.006) for USMLE Step 1. Learn about ATP7A mutations, defective copper absorption, and the role of Lysyl Oxidase in connective tissue defects. High-yield guide on mymedschool.org.

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U01.17.005 Ehlers-Danlos Syndrome (EDS) Flashcard: Collagen Defects

Master Ehlers-Danlos Syndrome (EDS) with our U01.17.005 high-yield flashcard. Learn about collagen types III and V, hypermobility, and vascular risks. Essential USMLE Step 1 biochemistry on mymedschool.org.

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