New Study Links Popular Thyroid Drug to Increased Bone Loss

A new study found that levothyroxine, a common medication for hypothyroidism sold as Synthroid, is linked to bone loss in older adults. Here's what experts think of the finding, and whether you should consider changing medications.

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Common Thyroid Medicine Linked to Bone Loss

Levothyroxine, prescribed for hypothyroidism, may be associated with bone loss in older adults, even when following current guidelines.

Levothyroxine is the second most commonly used prescription medication among older adults in the U.S.

Approximately 23 million Americans take #levothyroxine daily.

Th research is a collaboration between Johns Hopkins and the BLSA, the longest-running study on aging conducted by the Intramural Research Program of the National Institute on Aging #Bones #Health #MEdical #Aging #Thyroid

https://press.rsna.org/timssnet/media/pressreleases/14_pr_target.cfm?ID=2538

Common Thyroid Medicine Linked to Bone Loss

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#thyroid

#Levothyroxine taken at bedtime significantly improved thyroid hormone levels. Quality-of-life variables and plasma lipid levels showed no significant changes with bedtime vs morning intake. Clinicians should consider prescribing levothyroxine intake at bedtime.

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/776486#:~:text=In%20conclusion,%20bedtime%20intake%20of,more%20convenient%20for%20many%20patients.

Effects of Evening vs Morning Levothyroxine Intake: A Randomized Double-blind Crossover Trial

Background  Levothyroxine sodium is widely prescribed to treat primary hypothyroidism. There is consensus that levothyroxine should be taken in the morning on an empty stomach. A pilot study showed that levothyroxine intake at bedtime significantly decreased thyrotropin levels and increased...

The FDA Unapproved Drugs Initiative: An Observational Study of the Consequences for Drug Prices and Shortages in the United States - PubMed

This project was not supported by any external grants or funds. Gupta was supported by the Yale University School of Medicine Office of Student Research at the time of this study. Dhruva is supported by the Department of Veterans Affairs as part of the Robert Wood Johnson Foundation Clinical Scholar …

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