Mastodawn

Researchers try to cut the #genetic code from 20 to 19 #aminoacids
Using #AI tools, the team reworked part of the #ribosome to need one less #aminoacid.
Most hypotheses suggest that earlier forms of life had partial genetic codes and used fewer than 20 amino acids. A team from Columbia and Harvard eliminated one of 20 currently in use. As a first attempt, they engineered a portion of the ribosome that worked without using an otherwise essential amino acid: #isoleucine.
https://arstechnica.com/science/2026/04/researchers-try-to-cut-the-genetic-code-from-20-to-19-amino-acids/

Researchers try to cut the genetic code from 20 to 19 amino acids

Using AI tools, the team reworked part of the ribosome to need one less amino acid.

Ars Technica

AzureCerulean Apr 9, 2025

ScienceAlert: Cutting Back on Isoleucine an Amino Acid Increased Lifespan in Middle-Aged Mice Up to 33%

https://www.sciencealert.com/cutting-back-on-one-amino-acid-increased-lifespan-in-middle-aged-mice-up-to-33

#isoleucine

Cutting Back on One Amino Acid Increased Lifespan in Middle-Aged Mice Up to 33%

Research in mice showed limited intakes of one particular essential amino acid can slow the impacts of aging and even lengthen their lifespan.

ScienceAlert

neat_news Dec 13, 2024

In experiments with mice, researchers found that restricting the intake of a particular amino acid, called isoleucine, can increase the lifespan of middle-aged mice by up to a third. Isoleucine is found in eggs, soy, and meat. See http://www.neat-news.com/2024/12/302.php. #diet #lifespan #isoleucine

Neat News 2024

AzureCerulean Mar 20, 2024

Isoleucine

ScienceAlert: Cutting Back on One Amino Acid Increases Lifespan of Mice Up to 33%
https://www.sciencealert.com/cutting-back-on-one-amino-acid-increases-lifespan-of-mice-up-to-33

#thisonething #isoleucine

Cutting Back on One Amino Acid Increases Lifespan of Mice Up to 33%

Research in mice shows limited intakes of one particular essential amino acid can slow the impacts of aging and even lengthen their lifespan.

ScienceAlert

Matt Willemsen Jan 8, 2024

The Isoleucine Paradox: Eat More, Weigh Less, Live Longer
https://scitechdaily.com/the-isoleucine-paradox-eat-more-weigh-less-live-longer/ #Aging #Diet #Longevity #Metabolism #Isoleucine #AminoAcids #mice

The Isoleucine Paradox: Eat More, Weigh Less, Live Longer

New research from the University of Wisconsin School of Medicine and Public Health suggests that a calorie may not be just a calorie. There’s a popular saying in some circles that “a calorie is a calorie,” but science shows that it may not be true. In fact, it may be possible to eat more of some ki

SciTechDaily