Great talk by Nathanael Gray at #ISCPDD. He presented his group’s work on induced proximity to regulate transcription. Exciting data on recruiting a transcriptional activator (e.g. BRD4 or CDK9) to replace co-repressors on the death regulator BCL6 to induce cell death.

https://www.nature.com/articles/s41586-023-06348-2
#Chemistry #ChemBio #InducedProximity

Chemical Biology Postdoc in the Ferguson Lab at UCSD

University of California, San Diego

Join our team working on #TPD #InducedProximity as a Postdoctoral fellow in the Ferguson lab at UCSD

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-diego-27778-chemical-biology-postdoc-in-the-ferguson-lab-at-ucsd/?feed_id=91...
https://jobrxiv.org/job/university-of-california-san-diego-27778-chemical-biology-postdoc-in-the-ferguson-lab-at-ucsd/?feed_id=91018

Chemical Biology Postdoc in the Ferguson Lab at UCSD

University of California, San Diego

Join our team working on #TPD #InducedProximity as a Postdoctoral fellow in the Ferguson lab at UCSD

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-diego-27778-chemical-biology-postdoc-in-the-ferguson-lab-at-ucsd/?feed_id=90...
https://jobrxiv.org/job/university-of-california-san-diego-27778-chemical-biology-postdoc-in-the-ferguson-lab-at-ucsd/?feed_id=90738

#Introduction
I am a molecular biologist in the Protein Degradation group at GSK. I was trained in structural biology in my PhD. Got into chemical biology in my postdoc in Alessio Ciulli's  group in Dundee.
I am interested in targeted protein degradation and E3 ligase biology. Looking forward to read and share some interesting science on Mastodon.

#TPD #ChemicalBiology #Ubiquitin #InducedProximity #CRISPR