New complex immune dysregulation IEI:

DOCK11 deficiency

Presents with: cytopenia, systemic lupus erythematosus, skin, and digestive manifestations
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RT @FRLab1
Thrilled to share our latest article accepted in @BloodJournal, describing for the first time inherited DOCK11 deficiency #Immunodeficiencies #IEI https://ashpublications.org/blood/article-abstract/doi/10.1182/blood.2022018486/495065/DOCK11-deficiency-in-patients-with-X-linked
https://twitter.com/FRLab1/status/1640280637578829824

DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity

Key Points. DOCK11 deficiency is a new X-linked immune-related actinopathy.DOCK11 deficiency leads to impaired CDC42 activity, abnormal actin cytoskeleton remod

American Society of Hematology

I'm a vulnerable person who needs others to wear masks too. 😟

I've been stopped outside by randos who aggressively prevented me from walking to my destination & yelled at numerous times, just because I was wearing a #mask.

I even had a dude livestreaming me & laughing in addition. I kid you not.

I have multiple immunodeficiencies & need to wear a mask for other reasons too. I wore masks before the pandemic. This never happened then; I used to only get weird stares.

#MCAS #immunodeficiencies

I’m Megan from #ohio. I love #reading trashy novels and #taylorswift. I have #BipolarII, #immunodeficiencies, and #asthma. Also #queer 🌈