Serum Retinol but Not 25(OH)D Status Is Associated With Serum Hepcidin Levels in Older Mexican Adults [2019]
https://pmc.ncbi.nlm.nih.gov/articles/PMC6566922/
#IronDeficiency #anemia #hepcidin #VitaminA #inflammation #aging

Serum Retinol but Not 25(OH)D Status Is Associated With Serum Hepcidin Levels in Older Mexican Adults
(1) Background: Elevated hepcidin levels have been linked to anemia of inflammation (AI). Retinol deficiency has shown to upregulate hepcidin expression in animals, while conflicting evidence links VD status with hepcidin concentration in humans. ...
PubMed Central (PMC)Ferroportin is the only human iron exporter, suppressed by the peptide hormone
#hepcidin. The structure of
#ferroportin bound to hepcidin mimetic peptide PR73 reveals novel interactions and explains the enhanced affinity of PR73 @bcmhouston
#PLOSBiology https://plos.io/3ZKnwnJ
Structural basis of ferroportin inhibition by minihepcidin PR73
Ferroportin is the only known iron exporter in humans, and its suppressed by hepcidin, an endogenous peptide hormone. The structure of human ferroportin bound to the hepcidin mimetic peptide PR73 reveals interactions not seen in the hepcidin-ferroportin complex and provides a rationale for the enhanced affinity of PR73.
Ferroportin is the only human iron exporter, suppressed by the peptide hormone
#hepcidin. The structure of
#ferroportin bound to hepcidin mimetic peptide PR73 reveals novel interactions and explains the enhanced affinity of PR73 @bcmhouston
#PLOSBiology https://plos.io/3ZKnwnJ
Structural basis of ferroportin inhibition by minihepcidin PR73
Ferroportin is the only known iron exporter in humans, and its suppressed by hepcidin, an endogenous peptide hormone. The structure of human ferroportin bound to the hepcidin mimetic peptide PR73 reveals interactions not seen in the hepcidin-ferroportin complex and provides a rationale for the enhanced affinity of PR73.
Ferroportin is the only human iron exporter, suppressed by the peptide hormone
#hepcidin. The structure of
#ferroportin bound to hepcidin mimetic peptide PR73 reveals novel interactions and explains the enhanced affinity of PR73 @bcmhouston
#PLOSBiology https://plos.io/3ZKnwnJ
Structural basis of ferroportin inhibition by minihepcidin PR73
Ferroportin is the only known iron exporter in humans, and its suppressed by hepcidin, an endogenous peptide hormone. The structure of human ferroportin bound to the hepcidin mimetic peptide PR73 reveals interactions not seen in the hepcidin-ferroportin complex and provides a rationale for the enhanced affinity of PR73.