Mastodawn

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/25669765376050249/

Kosheeka Mar 24, 2025

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#hepatocytes #cellculture #primarycells #biotech #biotechnology #pharmaceuticals

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Kosheeka

PLOS Biology Oct 23, 2024

Hepatic #lipid #metabolism is regulated by the #AutonomicNervousSystem. This study shows that some #hepatocytes & cholangiocytes are innervated by branches of the vagus nerve; ablating them in mice on a high-fat diet prevents #HepaticSteatosis #PLOSBiology https://plos.io/4hdJiJp

The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet

The liver autonomic nervous system is regulated by hepatic lipid metabolism. This study shows that a subset of hepatocytes and cholagiocytes are innervated by nerve terminals originating from the dorsal motor nucleus of the vagus nerve in high-fat diet fed mice and ablation of these cholinergic neurons could prevent hepatic steatosis.

Julien Delpierre Aug 27, 2023

My Dresden colleagues have recently published a paper.

Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity

https://doi.org/10.15252/embr.202357181

https://twitter.com/ZerialLab/status/1686028788658847744?s=20