Mastodawn

Studying the data from almost 500 patients with Covid-19 it has been found that those patients that inhaled heparin had a significantly lower risk of dying compared to those who did not. The risk to require ventilation halved. See http://www.neat-news.com/3433.php. #Covid19 #heparin

Neat News

Neat News - Daily (not weekends) news about some positive development or insight.

bulbasaur4858 at KillBait Sep 30

Inhaled heparin shows significant benefits in reducing ventilation and mortality in COVID-19 patients

A recent international study led by the Australian National University in collaboration with King's College London has found that inhaled heparin significantly reduces the need for ventilation and lowers death risk in seriously ill COVID-19 patients. Heparin, traditionally used as an injectable anti... [More info]

RDN Sep 28

A randomized trial of 478 patients hospitalized for COVID-19 found that treatment with an inhaled form of heparin--which has antiviral and anti-inflammatory as well as anticoagulent properties--reduced the need for intubation by about half and reduced 28-day mortality by about two-thirds.

Summary: https://www.sciencedaily.com/releases/2025/09/250928095616.htm

Original paper: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00271-8/fulltext

#Science #COVID19 #Heparin

Doctors tested a common drug on COVID. The results are stunning

Inhaled heparin significantly lowers the risk of death and ventilation in COVID-19 patients while also showing potential against other respiratory infections. With its unique triple-action benefits, it could serve as a powerful and accessible treatment worldwide.

ScienceDaily

Jason Yip Apr 12, 2025

'Patients simply cannot survive': #Trump could wreck #SupplyChain for #heparin https://www.rawstory.com/tariff-2671754165/

'Patients simply cannot survive': Trump could wreck supply chain for critical drug

One of the potential unintended consequences of President Donald Trump's draconian new tariff regime on China could be the collapse of the supply chain to manufacture a vital and inexpensive drug necessary for hospitalized people, The Washington Post reported on Friday.Specifically, the anticoagulan...

Raw Story

FunGuy2PlayWith Apr 11, 2025

#WaPo Millions in the #US take this drug. #Tariffs might complicate their care.
#Heparin is cheap and essential...

"Experts say past events offer a preview of future risks. In 2008, a viral disease in pigs in #China caused a sudden shortage of the raw material used to make heparin. Some suppliers responded by mixing in cheaper, harmful substances, which led to 80 deaths and hundreds of serious side effects in the U.S."

#GiftedArticle

https://wapo.st/3EkqauC

Millions in the U.S. take this drug. Tariffs might complicate their care.

Heparin is cheap and essential to millions of hospitalized people. Tariffs could disrupt the supply chain that gets ingredients from China to their beds.

The Washington Post

micronicle.org Apr 9, 2025

Is it okay to start talking about a post 2020 'novel white clot syndrome' that echos a similar phenomena of the late 80s early 90s (search 'heparin white clot syndrome'). Can we talk about this without being cancelled now?
#whiteclotsyndrome #heparin #mRNA !!!

preLights Jan 7, 2025

Adriani Felix just posted two #preLights as part of a wonderful #preprint review initiative led by Marcus Oliveira #UFRJ

1️⃣ Adriani covers work from the Skidmore group, presenting BeHepI as a valuable tool for heparin quality control and structural analysis. Work that paves the way for safer and more effective blood thinners.

#preLight: https://prelights.biologists.com/highlights/enzymatic-access-to-the-rare-%ce%b4ua-1%e2%86%924-glc-3-6-n-sulfated-heparin-disaccharide-implications-for-heparin-quality-control/

#heparin #heparinase #biochemistry #medicine #anticoagulant #therapy

Enzymatic access to the rare ΔUA (1→4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control - preLights

Breaking barriers in anticoagulant research! BeHepI, a new enzyme, outperforms traditional methods by accurately analyzing key regions of heparin, paving the way for safer and more effective blood thinners.

preLights

Wirkstoffradio Dec 15, 2024

Neue Folge! WSR082 Blutgerinnung: Fibrin, Fibrinogen und die katalytische Triade mit Hans-Dieter Höltje und Bernd Rupp (@Rupi42ai). https://www.wirkstoffradio.de/2024/12/15/wsr082-blutgerinnung-fibrin-fibrinogen-und-die-katalytische-triade/ #Serinproteasen #Heparin #Blut

WSR082 Blutgerinnung: Fibrin, Fibrinogen und die katalytische Triade

In der Episode erläutern Hans-Dieter Höltje und Bernd Rupp die Mechanismen der Blutgerinnung, von der primären und sekundären Hämostase bis hin zur Rolle von Serinproteasen und Vitamin K in der Gerinnungskaskade.

Wirkstoffradio

Steve Dustcircle 🌹Jul 18, 2024

#Bloodthinning #drug #heparin may stop #snakebite victims losing limbs

https://www.newscientist.com/article/2439763-blood-thinning-drug-heparin-may-stop-snakebite-victims-losing-limbs/?utm_campaign=RSS%7CNSNS&utm_source=NSNS&utm_medium=RSS&utm_content=news

Blood-thinning drug heparin may stop snakebite victims losing limbs

Giving mice the blood-thinning drug heparin after they were injected with venom from two cobra species reduced their risk of tissue death, which can lead to amputations

New Scientist

neat_news Jul 18, 2024

More than 130,000 people a year are killed by snake bites, more than 400,000 injured. Now it has been found out in experiments with mice that in many cases of snake bites a drug commonly used to thin blood, heparin, can be an efficient antivenom to reduce the injuries from necrosis, or even prevent death. See http://www.neat-news.com/2024/07/196.php. #snake #heparin #antivenom