🚨 ALERT: Deadly Hendra virus returns to Queensland after 3 years!
Unvaccinated horse dies from bat-transmitted virus with 70% human mortality rate.
No human vaccine available. Health officials tracking exposures.
Read more to protect yourself 👇
Follow @karmactive for more updates
Two Novel Henipaviruses Detected in Fruit bats in China
The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
#bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
Umesh Prasad
Two Novel Henipaviruses Detected in Fruit bats in China
The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
#bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
Umesh Prasad
🔊 Ascolta articolo - An investigation launched after vials with deadly viruses such as Hendra and Hantavirus were discovered to have disappeared. The vials disappeared in 2021, but the discovery was not made until two years later There is a mystery in Australia over the disappearance of hundreds of vials containing potentially deadly viruses from […]
Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.00806-24?af=R
ABSTRACT
Batborne henipaviruses, such as Nipah and Hendra viruses, represent a major threat to global health due to their propensity for spillover, severe pathogenicity, and high mortality rate in human hosts. Coupled with the absence of approved vaccines or therapeutics, work with the prototypical species and uncharacterized, emergent species is restricted to high biocontainment facilities. There is a scarcity of such specialized spaces for research, and often, the scope and capacity of research, which can be conducted at BSL-4, is limited. Therefore, there is a pressing need for innovative life-cycle modeling systems to enable comprehensive research within lower biocontainment settings. This work showcases tetracistronic, transcription, and replication-competent minigenomes for the Nipah, Hendra, and Cedar viruses, which encode viral proteins facilitating budding, fusion, and receptor binding. We validate the functionality of all encoded viral proteins and demonstrate a variety of applications to interrogate the viral life cycle. Notably, we found that the Cedar virus replicase exhibits remarkable promiscuity, efficiently driving replication and transcription of minigenomes from all tested henipaviruses. We also apply this technology to Ghana virus (GhV), an emergent species that has so far not been isolated in culture. We demonstrate that the reported sequence of GhV is incomplete, but that this missing sequence can be substituted with analogous sequences from other henipaviruses. The use of our GhV system establishes the functionality of the GhV replicase and identifies two antivirals that are highly efficacious against the GhV polymerase.
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When I first learned to read in 3rd grade, recall doing a book report & attempting to answer the question “what most did you like about this book” w/ because it was long… My Ivy League cousins all laughed at me & wasn’t allowed to say that🙄
This book is super long🌈🌈
Wish more people would read it
#HendraVirus is interesting in that not many people possess #antibodies ..those that should that is
Made me think of my spouse who I promise you WAS exposed & getting these results pre-vaccines…🤔🧐🤨
If the birds rely on the food then stressing wildlife can sometimes increase the risk, i think this has been observed with #Hendravirus in #Flyingfoxes
The most important thing to get out of your garden is any domestic birds, it might be good to convert any breakfast layers into a Sunday roast. (Obviously only if you have the skill and facilities to do that safely and humanely, I'm half joking, contact an expert of some sort for advice.)
@harmonicarichard @jonashello @CdrHBiscuitIII @kirt @kirt
actually #Hendravirus and #ABLV #Lyssavirus are NOT mild in humans (50% to 100% mortality) but we manage to stop humans catching them very successfully!
so SARS-cov-2 infecting wild animals is not an excuse to give up.
this disinfo graphic still bugs me a year later… yes, eradication is doomed, but that's not an excuse to just give up completely and wallow in filth like the #NSW #LNP
@jonashello @harmonicarichard @CdrHBiscuitIII @kirt
Total eradication is probably impossible, descendants of pandemic variants have already got back into wildlife.
BUT being #Endemic in animals doesn't mean numerous human cases are inevitable.
#Australia has some horrifying endemic viruses including #Hendravirus and #ABLV (Aussie #rabies) but human cases of both are zero in most years. Even if these transmitted easily between humans, a swift response could contain infrequent outbreaks.
Karmactive
Umesh Prasad
Scientific European
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Lorraine
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Kirt