Biology OpenSuzuko Kinoshita et al. show that #Drosophila #haemocytes can recognise lymph gland #tumours and activate the innate #immune pathway in an ROS-dependent manner:
#Cancer #ROS #InnateImmunity #CellScience #BiologyOpen #AcademicMastodon #Biology #Science
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner
Summary:Drosophila hemocytes recognized disintegrated basement membrane of the LG tumors overexpressing MMP2 and stimulated ROS production to induce the anti-tumor peptides under innate immune pathway in the fat body.