Interesting study showing balance between bacterial & host factors determining granuloma formation and control of infection. This example being #Yersinia.
#granuloma #immunology #academia #Science #ScienceMastodon
Inflammatory monocytes promote granuloma control of Yersinia infection | Nature Microbiology
Such a neat story about bacterial virulence factor (EsxM) contributing to bone dissemination of TB disease through actions on macrophage motility. @cellpress
Unlikely to be the whole story, and it's taking a leap from zebrafish model to extrapolate human TB disease phenotype, but v plausible that bacterial manipulation of host immunobiology can alter natural history of #TB disease. #immunology #macrophages #granuloma #bone
https://www.cell.com/cell/fulltext/S0092-8674(22)01361-7?dgcid=raven_jbs_etoc_email
Il granuloma dentale è un'infiammazione cronica, generalmente asintomatica e non suppurativa, dell'apice radicale e dei suoi tessuti circostanti. Tipica complicanza silenziosa di carie, fratture o scheggiature dentali, il granuloma è dovuto essenzialmente ad un'invasione batterica proveniente dal canale radicolare. Sconfinando lentamente - ma progressivamente - nelle zone attigue, il granuloma in
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Gabriele Pollara
Medicina