I am not anti-science, but I do worry about GLP-1s. Styled as a kind of miracle cure for obesity, they just haven't been around long enough for us to see the long-term effects. This article is not reassuring.
"GLP-1s may also be reshaping parts of the brain.
"Tens of millions of people are now taking the medications worldwide, turning what began as an obesity and diabetes treatment into what could be modern medicine's largest unplanned neuroscience experiments.
...
"But not all of the reported mental effects of GLP-1 drugs have been positive. On social media and at doctor's offices, some users have reported a type of brain fog and others something broader and harder to define: a strange emotional flattening. People describe less pleasure, less motivation, diminished interest in hobbies and even reduced sexual desire.
"Those accounts are beginning to raise deeper questions about what, exactly, these drugs are changing. If GLP-1s alter the brain systems involved in reward, craving and motivation, researchers wonder, where is the line between quieting a person's destructive impulses and reshaping personality itself?"





