Darrer infectat de #ebola a #RDC surt guarit de l'hospital. Per darrera, 64 casos (53 confirmats, 11 probables) amb 45 morts, i una taxa de mortalitat per sobre del 66%. S'ha vaccinat a més de 35.000 persones. Cap cas nou des de fa gairebé un mes (concretament 25 setembre).

Comença el compte enrere de 42 dies per declarar #RDC lliure de #ebola altra cop... fins el proper brot.

#VaccinesWork #filovirus

https://www.afro.who.int/news/last-ebola-patient-democratic-republic-congo-discharged

Lack of #Lloviu Virus #Disease #Development in #Ferret Model

Source: Emerging Infectious Diseases Journal, https://wwwnc.cdc.gov/eid/article/30/12/24-0818_article

Abstract
The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a disease model for LLOV.

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#abstract #animalModels #filovirus #lloviuVirus #research

#Filovirus #vaccines as a #response #paradigm for emerging infectious diseases

Source: npj Vaccines, AbstractNowadays, filovirus vaccine development may be seen as a paradigm for our response capabilities to emerging and re-emerging infectious diseases. Specifically, the West African Ebola virus disease (EVD) epidemic accelerated countermeasure licensure for several vaccine and therapeutic products. Those products have been successfully used to control EVD outbreaks in…

https://etidioh.wordpress.com/2024/10/12/filovirus-vaccines-as-a-response-paradigm-for-emerging-infectious-diseases/

Source: US Centers for Disease Control and Prevention (CDC), HAN – Health Alert Network, https://emergency.cdc.gov/han/2024/han00517.asp?ACSTrackingID=DUSCDC_511-M137011&ACSTrackingLabel=HAN%20517%20-%20General%20Public&deliveryName=DUSCDC_511-M137011

{Health Advisory – Excerpt}

Summary
The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to inform clinicians and health departments about the Republic of Rwanda’s first confirmed outbreak of Marburg virus disease (MVD) with 36 laboratory confirmed cases and 11 deaths reported as of October 2, 2024, including at least 19 cases in healthcare workers. This report summarizes CDC’s recommendations for public health departments and clinicians in the United States on case identification and testing and clinical laboratory biosafety considerations. No confirmed cases of MVD related to this outbreak have been reported in the United States or other countries outside of the Republic of Rwanda to date. Currently, the risk of MVD in the United States is low; however, clinicians should be aware of the potential for imported cases.

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https://etidioh.wordpress.com/2024/10/03/first-marburg-virus-disease-outbreak-in-the-republic-of-rwanda/

#filovirus #marburg #rwanda #updates #USCDC #USA #viralHemorrhagicFever

Source: New Times, https://www.newtimes.co.rw/article/20610/news/health/marburg-virus-11-fatalities-reported-as-seven-new-cases-are-confirmed

{Excerpt}

The death toll from the Marburg virus increased to 11 after one person dies from the haemorrhagic disease on Wednesday, October 2, the Ministry of Health said. The health authorities also confirmed seven new cases, bringing the total to 36. As of Wednesday, 25 people were under isolation and treatment, the ministry said.

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https://etidioh.wordpress.com/2024/10/03/rwanda-marburg-virus-11-fatalities-reported-as-seven-new-cases-are-confirmed/

#filovirus #marburg #rwanda #viralHemorrhagicFever

Source: Africa CDC, https://africacdc.org/news-item/marburg-virus-disease-outbreak-in-rwanda/

ADDIS ABABA, Ethiopia, 1 October 2024 – The Ministry of Health of the Republic of Rwanda declared a Marburg virus disease (MVD) outbreak on 27 September 2024. As of 30 September, 27 confirmed cases and 9 deaths have been reported; most of the cases are health care workers. Over 297 contacts have been registered and are under follow-up.

The Ministry of Health is working tirelessly in collaboration with relevant partners to contain the deadly virus through enhanced preventive measures in all health facilities. Contact tracing is underway, and cases have been isolated for treatment. The Ministry of Health further urged Rwandans to remain vigilant and strengthen preventive measures by ensuring hygiene, washing hands with soap, sanitizing hands, and taking necessary precautionary measures when in contact with other individuals.

Marburg virus disease (MVD) is a severe and often fatal zoonotic haemorrhagic illness caused by the Marburg virus. The virus is usually transmitted to humans from fruit bats. Human-to-human transmission occurs through direct contact with an infected person’s body fluids, or with equipment and materials contaminated with infectious blood or tissues. There is currently no vaccine or specific treatment for MVD, so supportive therapy should be initiated immediately for any individuals presenting with the disease. The same infection prevention and control protocols used for other viral haemorrhagic fevers, such as Ebola, should be followed to prevent transmission.

On September 29th, the Africa Centers for Disease Control and Prevention (Africa CDC) dispatched a team of experts to aid in response efforts in Rwanda. Africa CDC is also collaborating with the Ministry of Health and neighbouring countries of Burundi, Uganda, Tanzania, and DR Congo to assist in addressing the cross-border aspects of the outbreak and to provide guidance on regional surveillance strategies to contain the outbreak.

The Minister of Health of Rwanda, H.E. Sabin Nsanzimana, will join the Africa CDC Press Briefing on Thursday, October 3, alongside the Director General of Africa CDC, Dr. Jean Kaseya, to discuss Rwanda’s efforts in curbing the Marburg virus.

About Africa CDC

The Africa Centres for Disease Control and Prevention (Africa CDC) is a continental autonomous public health agency of the African Union that supports member states in efforts to strengthen health systems and improve surveillance, emergency response, and prevention and control of diseases.

Learn more at: http://www.africacdc.org and connect with us on LinkedIn, Twitter, Facebook and YouTube

Media contacts:Margaret Edwin | Director of Communication and Public Information | [email protected]

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https://etidioh.wordpress.com/2024/10/02/marburg-virus-disease-outbreak-in-rwanda/

#filovirus #marburg #rwanda #updates #viralHemorrhagicFever

Source: Channels TV, https://www.channelstv.com/2024/10/02/toll-in-rwanda-marburg-outbreak-rises-to-11/

{Excerpt}

Five more people in Rwanda have died of the deadly Ebola-like Marburg disease, bringing the number of fatalities to 11, the health ministry said late Tuesday.

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https://etidioh.wordpress.com/2024/10/02/death-toll-in-rwanda-marburg-outbreak-rises-to-11/

#filovirus #marburg #rwanda #viralHemorrhagicFever