I am happy to share the unfinished but nevertheless fascinating autobiography of the late Thomas Cavalier-Smith, written in 2020, shortly before Tom passed away in 2021. I thank Ema Cavalier-Smith for sharing the text with me. I recently finished curating the text (small corrections and referencing) https://zenodo.org/records/18733367 #Evolution #Eukaryogenesis #biology #CellBiology

New #ISEPpapers! Eukaryotic Recombinases Duplicated After Divergence From Known Asgard Archaeal RadA: Implications for the Evolution of Sex During Eukaryogenesis https://academic.oup.com/gbe/article/17/12/evaf240/8402114 by Lisa Matsuo, @DacksLabECB

#Microbes #Archaea #AsgardArchaea #Eukaryogenesis

New #ISEPpapers! Eukaryote-Wide Distribution of a Family of Longin Domain-Containing GAP Complexes for Small GTPases https://onlinelibrary.wiley.com/doi/10.1111/tra.70016 by Anna NovΓ‘k VanclovΓ‘ et al.

#Protists #Microbes #Archaea #Eukaryogenesis #Evolution #Eukaryotes

New #ISEPpapers! Repeated duplications and losses shaped SMC complex evolution from archaeal ancestors to modern eukaryotes: Jolien van Hooff et al. https://www.sciencedirect.com/science/article/pii/S2211124725006266

#Protists #Microbes #Archaea #Eukaryogenesis #Evolution

#EukaryoticCells emerged as #evolutionary algorithmic phase transition: #Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer #proteins // #EvolutionaryBiology #ComputerBiology #evolution

https://nachrichten.idw-online.de/2025/04/17/the-eukaryotic-cell-emerged-as-an-evolutionary-algorithmic-phase-transition

The eukaryotic cell emerged as an evolutionary algorithmic phase transition

The eukaryotic cell emerged as an evolutionary algorithmic phase transition / Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer proteins / Evolvement of the eukaryotic cell is the most significant increase in complexity in the history of life's evolution on Earth πŸ‘‰ https://press.uni-mainz.de/eukaryotic-cell-emerged-as-evolutionary-algorithmic-phase-transition/

#EvolutionaryBiology #ComputerBiology #eukaryotic #genes #proteins #evolution #EukaryoticCells #eukaryogenesis #biology #physics

Eukaryotic cell emerged as evolutionary algorithmic phase transition | Press and Public Relations

Johannes Gutenberg University Mainz

Uncovering the Ancient Origins of Key Immune Machinery https://www.ualberta.ca/en/department-of-medicine/news-events/department-news/2024/10/joel-dacks-uncovering-the-ancient-origins-of-key-immune-machinery.html

Evolutionary origins of the #lysosome-related #organelle sorting machinery reveal ancient homology in post-#endosome trafficking pathways: Kiran More et al. https://www.pnas.org/doi/10.1073/pnas.2403601121

"the BLOC machinery plays an important role in #microbes today for our ecosystem and health and may help to explain the #evolution of the basic cellular configuration over 1.5 billion years ago."

#Protists #ImmuneSystem #Eukaryogenesis

Uncovering the Ancient Origins of Key Immune Machinery

New #ISEPpapers! Evolutionary origins of the lysosome-related organelle sorting machinery reveal ancient homology in post-endosome trafficking pathways: Kiran More et al. https://www.pnas.org/doi/10.1073/pnas.2403601121

#protists #microbes #CellBiology #eukaryogenesis #biology #organelles