Scientific FrontlineOct 16
#Lipids are fatty #molecules that play critical roles in cell function, including membrane structure, energy storage and nutrient absorption. Most lipids are made in a cell #organelle called the #endoplasmic reticulum, but specific lipid types are shuttled around to different parts of the cell depending on their purpose.
#Biochemistry #Biomolecular #sflorg
https://www.sflorg.com/2025/10/bchm10162501.html
The Many FACES of Lipid Research

A new technology will give unprecedented views of lipid movement inside cells

Scientific FrontlineOct 9
How #lipids in the membrane of the #endoplasmic reticulum of #plant cells interact with #proteins to organize the first step of protein transport has long been an unsolved mystery.
#Biology #sflorg
https://www.sflorg.com/2025/10/bio10092501.html
Old Puzzle around Protein Distribution in Plant Cells Solved

Researchers in Bochum have discovered a control mechanism that may also operate beyond plants.

The EMBO JournalOct 30, 2023
#UVRAG cooperates with cargo receptors to assemble the ER-phagy site
Yixian Cui and colleagues show that an #autophagy regulator promotes degradation of specific regions of the #endoplasmic reticulum independently of its role in #PI3KC3 complex II
https://www.embopress.org/doi/abs/10.15252/embj.2023113625
The EMBO JournalMar 21, 2023

Antitumor T-cell function requires #CPEB4-mediated adaptation to chronic #endoplasmic #reticulum stress

Raúl Méndez and colleagues at IRB Barcelona show that RNA-binding protein CPEB4 mediates transient unfolded protein response #UPR for stress adaptation in #CD8 #Tcells

https://www.embopress.org/doi/10.15252/embj.2022111494

CellBioNewsFeb 10, 2023

Researchers reveal #endoplasmic reticulum–associated #protein degradation and control of grain size in #rice.

#agriculture #ubiquitin #proteasome

https://phys.org/news/2023-02-reveal-endoplasmic-reticulumassociated-protein-degradation.html

Researchers reveal endoplasmic reticulum–associated protein degradation and control of grain size in rice

In a study published in The Plant Cell, researchers led by Li Yunhai at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences described a role for the endoplasmic reticulum (ER)–associated protein degradation in the regulation of grain size in rice (Oryza sativa).

Phys.org
The EMBO JournalDec 21, 2022
A link between #Smoothened #cholesterylation and #endoplasmic #reticulum exit in #Hedgehog signaling: #GRAMD1-mediated #cholesterol transfer and Smoothened modification accelerates it #COPII-dependent ER exit and promotes signaling
https://www.embopress.org/doi/10.15252/embj.2022111513