New Discovery Reveals Unconventional Mechanism of Cell Division in Embryos

📰 Original title: Textbooks challenged by new discovery about how cells divide

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👥 Usuarios: It's not clickbait ✅

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#science #celldivision #embryonicdevelopment #mechanicalratchet

New Discovery Reveals Unconventional Mechanism of Cell Division in Embryos

A team of scientists from Technische Universität Dresden has uncovered a surprising new mechanism for how large embryonic cells divide. This discovery challenges the long-held belief that a fully…

KillBait Archive

🌀 How does an embryo’s genome “wake up” and begin steering development on its own?

🔗 Long-range transcription factor binding sites clustered regions may mediate transcriptional regulation through phase-separation interactions in early human embryo. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.09.017

📚 CSBJ: https://www.csbj.org/

#GeneRegulation #EmbryonicDevelopment #ChromatinBiology #Epigenetics #DevelopmentalBiology #Genomics #CellBiology

"The process of sex reversal occurs during #EmbryonicDevelopment or before #GonadDifferentiation."
Bluesky

Bluesky Social
Scientists program stem cells to mimic first days of embryonic development

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists at UC Santa Cruz were able to create “programmable” cellular models of embryos without ever experimenting with any actual embryos.

UC Santa Cruz News

One of the great accomplishments of the space program had nothing to do with the science of space.

Instead, the impact came from the images and impressions that the astronauts sent back to Earth.
The most famous of these is “The Blue Marble,” an image of the earth from space taken in 1972.
It is one of the most reproduced images ever made, and it had (and continues to have) a powerful effect.
It’s a reminder that the home we share is small, isolated, and fragile. It is an example of how discovery and a new perspective have the power to bring us together.

It’s the same with embryonic development.
It is impossible to spend any time thinking about embryos without being filled with a profound sense of awe and connection.
The details of this shared experience are as foreign to most people as the image of the Earth was before 1972.
We are deeply interconnected with our fellow humans, and the animal world, through this shared rite of passage.
Embryonic development is a journey so fundamental to our lives that we cannot help but be bonded together through its details.

#fromonecell #embryonicdevelopment #benstanger

https://www.wildrumpusbooks.com/book/9781324076049

Why researchers should use human embryo models with caution
Scientists should carefully consider whether embryo models based on human stem cells are essential to their work because of the associated practical and ethical challenges.
#bioethics #researchethics #embryonicdevelopment
https://www.nature.com/articles/d41586-023-03062-x
Why researchers should use human embryo models with caution

Scientists should carefully consider whether embryo models based on human stem cells are essential to their work because of the associated practical and ethical challenges.

The right moves: How studying cell movement during embryonic development may offer new insights into cancer metastasis

Cancer's ability to spread throughout the body—a process known as metastasis—is responsible for the vast majority of cancer deaths. And a key feature of metastasis is that the cancer cells move, breaking away from a primary tumor and traveling to distant parts of the body.

Medical Xpress

What’s Next For Lab-Grown Human Embryos?
Researchers are now permitted to grow human embryos in the lab for longer than 14 days. Here’s what they could learn.

https://www.nature.com/articles/d41586-021-02343-7

#science #EmbryonicDevelopment #research

What’s next for lab-grown human embryos?

Researchers are now permitted to grow human embryos in the lab for longer than 14 days. Here’s what they could learn.

Rong, Zhou &co from the Key Laboratory of Marine Drugs at Ocean University of China show that genetic deletion of the heat shock factor hspa8 leads to selective tissue malformations in zebrafish embryonic development:
https://journals.biologists.com/jcs/article/135/21/jcs259734/278644/Genetic-deletion-of-hspa8-leads-to-selective
#cellbiology #research #zebrafish #embryonicdevelopment #ERstress
Genetic deletion of hspa8 leads to selective tissue malformations in zebrafish embryonic development

Summary: Hspa8 (also known as Hsc70), an essential protein for cell survival, has tissue-specific roles via induction of the unfolded protein response in the regulation of zebrafish embryonic development.

The Company of Biologists

Thigh bone #evolution got dinos up on two feet
https://www.futurity.org/dinosaurs-evolution-bipedalism-bones-2835102/

The dinosaurian femoral head experienced a morphogenetic shift from torsion to growth along the avian stem https://royalsocietypublishing.org/doi/10.1098/rspb.2022.0740

They figured out the way in which the femoral head, a critical part of #dinosaurs #anatomy, developed. Inward-turned femoral heads are necessary for fast, effective bipedal locomotion. Its #EmbryonicDevelopment changed completely—even while the feature itself remained constant in adults.

Thigh bone evolution got dinos up on two feet

Researchers have charted the evolution of the leggy alterations that allowed dinosaurs and birds to stand on their own two feet.

Futurity