Researchers have established a novel line of #bovine #embryonic stem cells (#ESCs ) derived from the blastocyst stage that maintain a stable, formative pluripotent state.
#AgriculturalScience #AnimalScience #Biotechnology #sflorg
https://www.sflorg.com/2026/02/agri02042601.html
New Line of Bovine Embryonic Stem Cells Shows Promise for Lab-Grown Meat, Biomedical Applications

Among the first labs in the world to develop bovine embryonic stem cells before, the UConn team’s work has distinct advantages

#Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early #embryonic development have remained elusive – particularly for egg-laying species.
#Biochemistry #Biology #sflorg
https://www.sflorg.com/2026/01/bchm01072601.html
The Mechanical Ratchet: A New Mechanism of Cell Division Uncovered

In most species, cells divide by forming a contractile ring from a structural protein known as actin at the cell equator.

Fetal #cells can be traced back to the first day of #embryonic development.

#blastomeres

https://phys.org/news/2024-05-fetal-cells-day-embryonic.html

Fetal cells can be traced back to the first day of embryonic development

Though more than 8 million babies have been born through in vitro fertilization (IVF), 70% of IVF implantations fail. As IVF is becoming a more common route to pregnancy in cases of infertility, there is a need for better understanding of embryonic development at this early stage.

Phys.org
Scientists discover pressure determines which embryonic cells become 'organizers'

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children's in Los Angeles has identified a mechanism by which embryonic cells organize themselves to send signals to surrounding cells, telling them where to go and what to do. While these signaling centers have been known to science for a while, how individual cells turn into organizers has been something of a mystery.

Phys.org
A mechanism identified by which #embryonic cells organize themselves to send signals to surrounding cells, telling them where to go and what to do. While these signaling centers have been known to science for a while, how individual cells turn into organizers has been something of a mystery.
#Biology #sflorg
https://www.sflorg.com/2024/04/bio04032402.html
Pressure determines which embryonic cells become ‘organizers’

Seeing how pressure works in embryonic development opens up further research possibilities

Scientists show how the signaling molecules BMP and FGF guide cell differentiation during embryonic development

Bricklayer, banker, teacher—choosing a career is one of the most exciting and important decisions in our lives. At the beginning of embryonic development, our cells are also faced with this decision. Some of them become blood cells, others muscle cells and still others become nerve cells.

Phys.org

"Here, we examine changes in rRNA 2′-O-me during mouse brain development and tri-lineage differentiation of human #embryonic stem cells (hESCs). We find distinct alterations between #brain regions, as well as clear dynamics during cortex development and germ layer differentiation. We identify a #methylation site impacting #neuronal #differentiation."

https://www.sciencedirect.com/science/article/abs/pii/S1534580723003052?via%3Dihub

Number of #DNA copies influences the #cell #death process that shapes organs during #embryonic development: Study.

#autophagy #polyploidy

https://phys.org/news/2023-07-dna-cell-death-embryonic.html

Number of DNA copies influences the cell death process that shapes organs during embryonic development: Study

During embryonic development, the programmed death of certain cells plays an essential role in shaping organs and allowing proper growth. This cell death is in some cases an effect of autophagy, a key cellular process responsible for the degradation and recycling of damaged or unwanted cellular components and which, taken to the extreme, may end up eliminating the cell itself.

Phys.org
How a worm's embryonic cells change its development potential

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

Phys.org