Our recent Perspective on extrachromosomal circular DNA is the focus of December's GBE Highlight.
Highlight: Running Circles Around Genome Architecture
🔗 https:/doi.org/10.1093/gbe/evaf232
This is our first Highlight produced under the SMBE Fellows Program, written by Shady A. Kuster.
From 2022:
Extrachromosomal circular DNA: A neglected nucleic acid molecule in plants.
#ExtrachromosomalCircularDNA #eccDNA #Transposons #PlantScience
https://www.sciencedirect.com/science/article/pii/S1369526622000929
A comprehensive atlas of full-length Arabidopsis eccDNA populations identifies their genomic origins and epigenetic regulation.
#ExtrachromosomalCircularDNA #eccDNA #Transposons #Arabidopsis #MethylationMutants #LongReadSequencing
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003275
Previous studies of extrachromosomal circular DNA (eccDNA) in plants are based on short-read sequencing and cannot efficiently identify their full-length, generated from transposable elements. This study uses long-read sequencing to obtain a comprehensive map of full-length eccDNAs from Arabidopsis and identifies their genomic origins and epigenetic regulation.
#DNA element with a murky past is borrowing cell's #repair machinery.
#retrotransposon #parasite #alt_EJ #eccDNA
https://phys.org/news/2023-07-dna-element-murky-cell-machinery.html
GenomeBiolEvol
Amelia Cervera 🧬
PLOS Biology
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