Benjamin Carr, Ph.D. 👨🏻‍💻🧬Mar 27
New #antibiotic that kills #drugresistant #bacteria discovered in technician’s #garden
It targets bacteria’s protein-making factory, the #ribosome, in a way that other antibiotic drugs don’t. Ribosome is an attractive antibiotic target because bacteria don’t easily develop resistance to #drugs targeting the structure. In studies, #lariocidin slowed the growth of a range of common bacterial #pathogens, including many multidrug-resistant strains.
https://www.nature.com/articles/d41586-025-00945-z
https://archive.ph/NHtJh
New antibiotic that kills drug-resistant bacteria discovered in technician’s garden

The molecule targets bacteria in a way that other drugs don’t.

Punk Metal n BowieJan 11
Livescience.com: 'Wake-up call' as #hookworm #parasites that infect pets and people grow #drugresistant
https://www.livescience.com/health/viruses-infections-disease/wake-up-call-as-hookworm-parasites-that-infect-pets-and-people-grow-drug-resistant
'Wake-up call' as hookworm parasites that infect pets and people grow drug resistant

Hookworms that cause deadly dog infection and 'creeping eruption' in humans are growing resistant to drugs.

Live Science
Daniel Hoffmann 🥬Nov 15

More artemisinin resistant malaria in children with severe infection.

Fears for spread of malaria in Africa as study finds resistance to frontline drug
https://www.theguardian.com/global-development/2024/nov/14/malaria-study-drug-resistance-children-disease-africa-research-artemisinin

#artemisinin #drugresistant #malaria

Fears for spread of malaria in Africa as study finds resistance to frontline drug

Signs of resistance to artemisinin in tenth of children with severe malaria similar to situation in Asia, say researchers

The Guardian
Knowledge ZoneOct 27, 2024

Just One #Tree : Medium

40 million #Deaths by 2050: toll of #DrugResistant #Infections to rise by 70% : Nature

#PolarBears adapted to the #Arctic just 70,000 years ago : Pop Sci

Check our latest #KnowledgeLinks

https://knowledgezone.co.in/resources/bookmarks

Bookmarks

Knowledge Zone Bookmarks - Links to latest articles

Knowledge Zone
ehwozaSep 20, 2024
It was while she was in a clinic in Cape Town, enduring the complicated, agonizing treatment for extremely #drugresistant #tuberculosis, that Phumeza Tisile began to question why “there weren’t better medications that had less side effects.” https://www.devex.com/news/fighting-drug-resistant-tb-was-costly-here-s-how-that-s-changed-108180
Show threadLorraineMay 20, 2024

https://www.cidrap.umn.edu/antimicrobial-stewardship/drug-resistant-trichophyton-fungus-represents-emerging-threat-us
#Trichophytonindotinea #Tindotineae #drugResistant #fungus #fomites #mold #ImmuneDysregulation #everythingIsFine
Every time they say rare these days….🤨🚨🚨🚨
Maybe it’s just a me thing, BUT RAMPANT FUNGUS FREAKS ME OUT🤦🏻‍♀️

If you stop the primary problem… usually it alleviates secondary issues🙄

Drug-resistant Trichophyton fungus represents emerging threat in US

CIDRAP
CurrentBiasApr 29, 2024

"Herein, we describe the clinical case of an immunosuppressed host in whom inadequate treatment resulted in highly diverse SARS-CoV-2 mutations that threatened the patient’s health due to the development of drug-resistant variants."

https://www.nature.com/articles/s41467-024-47941-x

#SARSCoV2 #covid #covid19 #antiviral #DrugResistant #PublicHealth

Dynamic diversity of SARS-CoV-2 genetic mutations in a lung transplantation patient with persistent COVID-19 - Nature Communications

In this study, the authors report the case of a patient who underwent lung transplantation and subsequently developed COVID-19 that resulted in persistent infection. Following antiviral treatment, SARS-CoV-2 (BA.5) showed dynamic genetic diversity with remdesivir resistant mutations leading to enhanced fusogenicity.

Nature
Benjamin Carr, Ph.D. 👨🏻‍💻🧬Mar 28, 2024
#China has a big #STD problem with #supergonorrhea, study finds
#DrugResistant #gonorrhea is a growing problem—one that doesn't heed borders
Study surveyed gonorrhea—Neisseria gonorrhoeae—from around China and found prevalence of #ceftriaxone-resistant isolates nearly tripled between 2017 and 2021. Ceftriaxone-resistant strains made up roughly 8% of the nearly 3,000 bacterial isolates collected from gonorrhea infections in 2022. That's up from just under 3% in 2017.
https://arstechnica.com/science/2024/03/super-gonorrhea-rate-quickly-triples-in-china-now-40x-higher-than-us/
China has a big problem with super gonorrhea, study finds

Drug-resistant gonorrhea is a growing problem—one that doesn't heed borders.

Ars Technica
DoomsdaysCWDec 5, 2023

Experts sound the alarm over #drugresistant #fungal infection detected in US

Story by Matthew Dooley, December 4, 2023

"Experts are sounding the alarm about a highly contagious #fungaldisease that's becoming resistant to common drugs. They warn this could make illnesses like #thrush much harder to treat.

"Medical professionals have warned that the world is not prepared for the growing threat of fungal infections.

"These can range from common conditions like #ringworm and thrush to life-threatening bloodstream infections caused by #CandidaAlbicans and #CandidaAuris.

"David Denning, a professor at the University of Manchester, previously spoke to The Mirror about a drug-resistant form of #ringworm. He explained how this fungus can easily spread in schools and homes.

"He said: 'Skin fungal infections are transmitted from one person to another in schools, homes and with intimate contact. This new #TerbinafineResistant fungus is a new species called #TrichophytonIndotineae and [was] first identified in India.

"Experts believe the rise in resistant fungi is due to overuse of over-the-counter #antifungal creams, misuse of #TopicalSteroid creams, incorrect prescription of antifungal drugs, as well as patients not sticking to prescribed courses of antifungal medication."

Full article: https://www.msn.com/en-us/health/medical/experts-sound-the-alarm-over-drug-resistant-fungal-infection-detected-in-us/ar-AA1kYAGN?rc=1&ocid=winp1taskbar&cvid=385d94e96b274f72942909e01780ddbc&ei=5

#Fungal #DrugResistance

MSN

Technische Universität MünchenNov 2, 2023

Smartbax, one of our spinoffs, is nominated for a Science Breakthrough award at the Falling Walls summit! 🎉 The researchers are developing #antibiotics against #drugresistant bacteria: https://go.tum.de/450394 🔬🦠

#Entrepreneurship #startup

đź“·smartbax

Start-up dedicated to developing new antibiotics

The start-up smartbax, which is developing new antibiotics, is nominated for Science Breakthrough of the Year at the Falling Walls Summit.