Vandaag 10 jaar geleden https://sailing-dulce.nl/home/article-4726 #kerstdiner #warmstekerst #docetaxel #overleving Zaterdag 26-12-2015, 2e Kerstdag Het is alweer even geleden dat we aan een kerstdiner aanzaten. Ik heb het opgezocht; de laatste keer was in 2009 op 2e kerstdag met alle overwinteraars in Aghios NikolΓ‘os op Kreta. Het kerstdiner gisteravond bij Derrick & Nicky in Oostzaan was uitstekend geregeld en erg gezellig. Alle kinderen en kleinkinderen van Ans aanwezig, Sue (de moeder van Nicky, drie andere..
πŸ’ŠπŸ’‰ #docetaxel SmPC for Docetaxel Hospira 10 mg/mL concentrate for solution for infusion has been updated with changes to sections 4.2 Posology; 5.1 Pharmacodynamic; 5.2 Pharmacokinetic; 6.3 Shelf life; 6.4 Special precautions for storage; 7. Marketing authorisation holder; Revised: 04/2024 Ref: gxDL 7_0. 🌐 https://www.medicines.org.uk/emc/product/5762/smpc Change log: https://www.medicines.org.uk/emc/product/5762/smpc/history
Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc)

Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) by Hospira UK Ltd

πŸ’ŠπŸ’‰ #docetaxel SmPC for Docetaxel Hospira 10 mg/mL concentrate for solution for infusion has been updated with changes to sections 4.4 Special warnings; 4.6 Fertility, pregnancy; 4.8 Undesirable effects; 5.1 Pharmacodynamic; 5.2 Pharmacokinetic; 5.3 Preclinical safety data; Revised: 12/2023 Ref: gxDL 6_1. 🌐 https://www.medicines.org.uk/emc/product/5762/smpc Change log: https://www.medicines.org.uk/emc/product/5762/smpc/history
Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc)

Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) by Hospira UK Ltd

How does breast cancer recur after dormancy? @TTCooperPhD & @DrPostovit explore a #PLOSBiology study showing that #docetaxel-induced injury of #tumor stromal cells stimulates release of #cytokines that support dormancy escape of #BreastCancer cells. Paper: https://plos.io/3RjsGoQ Primer: https://plos.io/457Epuh
Taxane chemotherapy induces stromal injury that leads to breast cancer dormancy escape

Cancer dormancy is a major hindrance to achieving complete clinical response in patients. This study uses a tumor stromal organoid and murine breast cancer model to reveal that chemotherapy injures stromal cells, but not dormant cancer cells directly; this stromal injury in turn invokes proinflammatory cytokine signaling and can awaken dormant cancer cells.

I'm now keeping an eye on: The SmPC for Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion

🏭Hospira UK Ltd

πŸ’ŠπŸ’‰ #docetaxel.

I will let you know if it changes.

🌐 https://www.medicines.org.uk/emc/product/5762/smpc

Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc)

Docetaxel Hospira 10 mg/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) by Hospira UK Ltd

Our #STOPCAP #IPDMA of #docetaxel for advanced #prostateCancer #mHSPC came out this week in #LancetOncology!

Very excited about this: result of tremendous collaborative effort to obtain harmonized trial data, apply meticulous checking & processing, and carry out high-quality statistical analysis. Aim was to clarify patterns of survival within patient subgroups most & least likely to benefit.

https://doi.org/10.1016/S1470-2045(23)00230-9