Saturday morning, third cup of strong coffee. Getting ready for 2 helpers to arrive, the sisters we’ve been lucky to have for 3 years. I have such a list for them (and me too) and as usual, a way too optimistic goal. Yet, better to plan big than too little. They come back tomorrow as well.

Obviously the caffeine kicked in for I was able to read this article/journal about the identification of the bones of some sailors from 2 expedition ships from England to Canada (Nunavut) in 1845. The use of DNA testing and procedures was truly astonishing to me. Combined with genealogy, historical data and previous archaeological studies, just 4 of the 105 or so sailors who died there after the ships were icebound were identified from bones.

Oh my, the horror of 3 years’s survival for these sailors. Yet, what an effort. I did learn a lot this morning and am again grateful I had a good education and both in high school and college so I actually can understand remarkable advances in science. I couldn’t stop reading and past the scientific testing details a history and picture of who these men and their families and descendants are memorable.
#GoScience #Science #DNA #DNAResearch #History

https://www.sciencedirect.com/science/article/pii/S2352409X26001744

🔬 Un salto avanti nella scienza: un sensore che permette di osservare il DNA ripararsi in tempo reale! #TechAdvance #DNAResearch

🔗 https://www.tomshw.it/scienze/dna-danneggiato-e-riparato-prime-immagini-live-2025-11-24

Un sensore mostra il DNA che si ripara in tempo reale

Un nuovo sensore fluorescente permette di seguire in tempo reale come il DNA si danneggia e si ripara, rivoluzionando gli studi su cancro e invecchiamento.

Tom's Hardware
Why Great White Sharks’ DNA Doesn’t Add Up

Great white sharks hold a baffling genetic puzzle: uniform nuclear DNA but divided mitochondrial DNA that defies migration and evolution theories. White sharks show a striking mismatch between the DNA inside their cell nuclei and the DNA within their mitochondria. For years, scientists believed this could be explained by the way great whites migrate. A [...]

Pure Science News
'Dark DNA' may explain dancing spiders' extraordinary diversity

There are many more species of peacock spider than other animals, scientists think they may know why.

Cancer DNA is detectable in blood years before diagnosis

Tiny, newly formed tumors shed small fragments of DNA that are swept into the bloodstream. Future cancer screening tests could detect them early.

Science News
Africa: African Wild Dogs - DNA Tests of Their Faeces Reveal Surprises About What They Eat: [The Conversation Africa] The African wild dog is one of Africa's most endangered predators. African wild dogs are highly elusive, avoiding human contact and utilising vast, remote territories to remain out of sight. Current estimates suggest that only about 6,600 individuals remain, in… http://newsfeed.facilit8.network/TKYfQ7 #WildlifeConservation #AfricanWildDogs #EndangeredSpecies #DNAResearch #AnimalBehavior
The Mysterious Yeti : The Abominable Snowman || Speeches N Stories

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The Mysterious Yeti : The Abominable Snowman || Speeches N Stories

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🧬💥 Did you know double-stranded DNA (dsDNA) viruses like herpesviruses depend heavily on a key host’s enzyme for replication? Discover how Sebastian Zeltzer, Pierce Alyn Longmire, Marek Svoboda, Giovanni Bosco, and Felicia Goodrum uncovered a surprising role of host DNA in maintaining viral genome stability. Learn more at https://doi.org/10.25422/azu.data.19127993 and https://doi.org/10.1073/pnas.2203203119 Image: Zeltzer et al. (2022). CC0 #Opendata #OpenScience #Virology #DNAResearch #UniversityOfArizona
Alignment data for "Host translesion polymerases are required for viral genome integrity"

Human cells encode up to 14 DNA polymerases with specialized functions in chromosomal DNA synthesis and damage repair. By contrast, complex DNA viruses, such as those of the herpesviridae family, encode a single high-fidelity DNA polymerase. This disparity raises the possibility that DNA viruses may rely on host polymerases for synthesis through complex DNA geometries. We tested the importance of error-prone Y-family polymerases involved in translesion synthesis (TLS) to human cytomegalovirus (HCMV) infection. We find most Y-family polymerases involved in the nucleotide insertion and bypass of lesions restrict HCMV genome synthesis and replication. By contrast, other TLS polymerases, such as the polymerase z complex, which extends past lesions, was required for optimal genome synthesis and replication. Depletion of either the polz complex or the suite of insertion polymerases demonstrate that TLS polymerases suppress the frequency of viral genome rearrangements, particularly at GC-rich sites and repeat sequences. Moreover, while distinct from HCMV, replication of the related herpes simplex virus type 1 (HSV-1) is impacted by host TLS polymerases, suggesting a broader requirement for host polymerases for DNA virus replication. These findings reveal an unexpected role for host DNA polymerases in ensuring viral genome stability. These data represent alignments used for Fig. 5 of the associated publication. Also included is a TB40E reference genome. Refer to the README.rtf file in Alignments.zip for further information.  For inquiries regarding the contents of this dataset, please contact the Corresponding Author listed in the README.txt file. Administrative inquiries (e.g., removal requests, trouble downloading, etc.) can be directed to [email protected]

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