Mastodawn

🚀 "Databricks has generously open-sourced #Dicer, their new #auto-sharder, so you too can experience the joy of dividing your data into tiny, useless fragments! 🎉 Meanwhile, they drown you in #buzzwords and partner programs nobody asked for, but hey, at least it's 'open' 😂."
https://www.databricks.com/blog/open-sourcing-dicer-databricks-auto-sharder #Databricks #open-source #dataengineering #technews #HackerNews #ngated

Open Sourcing Dicer: Databricks’ Auto-Sharder

Open sourcing Dicer, Databricks’ auto sharder. Learn why auto sharding matters, how Dicer works, and how it keeps Unity Catalog and SQL fast through restarts.

Databricks

Hacker News Jan 13

Open sourcing Dicer: Databricks's auto-sharder

https://www.databricks.com/blog/open-sourcing-dicer-databricks-auto-sharder

#HackerNews #OpenSourcing #Dicer #Databricks #AutoSharder #DataEngineering #BigData

Open Sourcing Dicer: Databricks’ Auto-Sharder

Open sourcing Dicer, Databricks’ auto sharder. Learn why auto sharding matters, how Dicer works, and how it keeps Unity Catalog and SQL fast through restarts.

Databricks

Aleksandra Stęplowska Jan 4, 2024

The accepted (before proof) version of our first #2024 #article is available online:

The #Dicer-like Protein 4 and RNA-dependent RNA Polymerase 6 are Involved in Tomato Torrado #Virus Pathogenesis in #Nicotiana benthamiana

Published in #Plant and #Cell #Physiology and funded by #NCN #Sonata

https://academic.oup.com/pcp/advance-article-abstract/doi/10.1093/pcp/pcad169/7510585?redirectedFrom=fulltext&fbclid=IwAR0b7Nf_S6h979nUqnTqCZV8i11wlKEWRdxgVtvFc65v5SV12DuzmoM20tY&login=false

#science #plantscience #plantvirus #virology #plantvirusinteraction #PTGS #RNAi #torradovirus

The Dicer-like Protein 4 and RNA-dependent RNA Polymerase 6 are Involved in Tomato Torrado Virus Pathogenesis in Nicotiana benthamiana

Abstract. Tomato torrado virus (ToTV) is a type member of the Torradovirus genus in the Secoviridae family known to cause severe necrosis in susceptible tomato

OUP Academic

Sterling Ericsson Mar 19, 2023

DICER is one of the fundamental enzymes in your body, responsible for processing RNA into different forms, often involved with RNA silencing.

While we know how double stranded RNAs are processed, how DICER processes microRNAs is poorly understood.

Now, Seoul National University scientists have identified how it utilizes the GYM motif for processing, expanding our fundamental understanding.

#Biology #Microbiology #Genetics #RNA #Dicer #miRNA #Science #Scicomm

https://www.nature.com/articles/s41586-023-05723-3

Structure of the human DICER–pre-miRNA complex in a dicing state - Nature

The active-state structure of human DICER bound to pre-miRNA reveals the structural basis for the specificity of DICER in how it selects substrates in a sequence dependent manner, and sheds light on DICER-related diseases.

Nature

CellBioNews Mar 3, 2023

Previously unknown mechanism in precision #RNA #cleaving by #Dicer #enzyme revealed.

#miRNA #siRNA

https://phys.org/news/2023-03-previously-unknown-mechanism-precision-rna.html

Previously unknown mechanism in precision RNA cleaving by Dicer enzyme revealed

Researchers at the Center for RNA Research, Institute for Basic Science (IBS), in Seoul, have published a study with critical new insights into the structure and function of the Dicer enzyme. Dicer is an enzyme required for the biogenesis of miRNAs and small interfering RNAs (siRNAs), which in turn are drivers of RNA silencing and post-transcriptional regulating of gene expression, one of the bodies' many checks on protein production.

Phys.org