DNA demethylation explains how tomatoes convert their bitter toxins into something more palatable

A multi-institutional team of bioengineers has identified the genetic mechanism that converts bitter toxins to palatable compounds in tomatoes. In their study published in the journal Science Advances, the group analyzed whole-genome bisulfite sequencing data obtained through other research efforts and conducted experiments in their lab that involved blocking the production of certain proteins to learn how tomatoes make themselves taste better to seed dispersers.

Phys.org

Cotranscriptional #demethylation induces global loss of #H3K4me2 from active genes in #Arabidopsis

@TetsujiKakutani Soichi Inagaki @soinagak Shusei Mori and colleagues show that histone #demethylase LDL3 travels with RNA polymerase II, leaving a record of gene transcription

https://www.embopress.org/doi/full/10.15252/embj.2023113798

Lineage commitment of #dermal #fibroblast #progenitors is controlled by #Kdm6b-mediated #chromatin #demethylation
Ryan Driskell and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2023113880
Lineage commitment of #dermal #fibroblast #progenitors is controlled by #Kdm6b-mediated #chromatin #demethylation
Ryan Driskell and coworkers @DriskellLab
https://www.embopress.org/doi/full/10.15252/embj.2023113880
Lineage commitment of #dermal #fibroblast #progenitors is controlled by #Kdm6b-mediated #chromatin #demethylation
Ryan Driskell and coworkers @DriskellLab
https://www.embopress.org/doi/full/10.15252/embj.2023113880
🧬🌿As part of our recent special issue, Zhang et al. discuss the past, present, and future of #DNA #demethylation in plants--from the discovery of #ROS1 in #Arabidopsis to #epigenome editing for #crop breeding and #GeneTherapy🔓⬇️ #PlantScience #PlantBiology
https://doi.org/10.1111/jipb.13423
@wileyplantsci
#PlantSci