Prevalence of Post-COVID Symptoms Across Variants of Concern and Follow-up Periods: A Systematic Review and Meta-Analysis
https://www.ijidonline.com/article/S1201-9712(26)00157-8/abstract
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#Coronavirus
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"We found that long-forgotten plagues have roared back, killing and maiming children in parts of the world where access to vaccines or trust in them faltered. What seemed like subtle changes to a country’s vaccine policies had disastrous consequences years later."
https://www.propublica.org/article/rfk-jr-vaccine-agenda-childhood-plagues
#PublicHealth #vaccines #immunizations #disabilities #measles #meningitis #covid #smallpox #diphtheria #tetanus #rubella #polio #HHS #CDC #ACIP #mistrust #misinformation #gavi #GlobalHealth
The health secretary is spreading doubts about vaccine safety and considering changes that could prompt manufacturers to flee the U.S. market. History has shown how plagues from the past can roar back when trust in shots — or access to them — falters.
A Haitian-born man from Fort Lauderdale, Florida, was stripped of his U.S. citizenship after defrauding COVID-19 relief programs of millions and lying during the naturalization process, federal prosecutors said.
This paper: https://pubs.acs.org/doi/10.1021/acschemneuro.5c00478
Our results indicate that [COVID Spike proteins] can [...] cause lipid vesicle leakage and exhibit increased toxicity to neuroblastoma cells
and
our findings raise compelling questions about the potential role of SARS-CoV-2 infection in accelerating or triggering neurodegenerative diseases linked to protein amyloidosis
...
Emerging evidence suggests that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have long-term deleterious effects on the central nervous system and even contribute to post-COVID neurological syndromes
...
Several theoretical and experimental studies have suggested that certain proteins from the SARS-CoV-2 virus can promote, either directly or indirectly, the formation of amyloid aggregates. For instance, the S1 domain of SARS-CoV-2, which includes the fragment S194, has been shown to interact with αSyn, inducing the formation of protein aggregates capable of causing synaptic damage and cytotoxicity
...
H1N1 infection has been reported to [...] increasing susceptibility to neurodegeneration
#COVID #COVID19 #SARSCoV2 #neurodegeneration #neurology #nueroscience #CovidIsNotOver
Emerging evidence suggests that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have long-term deleterious effects on the central nervous system and even contribute to post-COVID neurological syndromes. Interestingly, inflammation-induced proteolytic processing of the Spike protein of SARS-CoV-2 leads to the generation of peptides capable of aggregating into amyloid fibrils in vitro. Herein, we investigate the in vitro effect of a fibrillogenic fragment of the Spike protein [Spike 194–203 (S194)] on the aggregation and toxicity of the Parkinson’s disease (PD) protein α-synuclein (αSyn). Our results indicate that S194 fibrils stimulate in a concentration-dependent manner the fibrillation of αSyn monomer, resulting in aggregates with increased capacity of inducing lipid vesicle leakage and toxicity to neuroblastoma cells, in comparison with either αSyn or S194 alone. Bidimensional NMR (1H–15N-HSQC) suggests that S194 fibrils cause a higher perturbation in both the N-terminal region (sequence: 19–68) and the hydrophobic central domain of the αSyn monomer (sequence: 71–95), which is corroborated by protein–peptide docking and molecular dynamics simulations. In contrast with fibrils from wild-type αSyn, aggregates from the PD variant A30P exhibited a remarkable accelerative effect on S194 fibrillation. Similarly, fibrils from amyloid-β peptides, which are linked to Alzheimer’s disease, exhibited a pro-aggregating effect on the S194 monomer. Taken together, these findings might contribute to a broader understanding of the potential connections between SARS-CoV-2 infection and amyloid-related neurodegenerative disorders, highlighting areas that may warrant further investigation.
In #NYC as of March 14, #COVID and #RSV cases are down, and so are #RSVirus emergency department visits as a percentage of all ED visits. #influenza cases and #COVID19 and flu ED visits are slightly up, but it's all within normal fluctuations.
No new COVID deaths were reported, so we're on track for another relatively low-death month.
But #COVIDIsNotOver as long as people are going to hospitals and dying, so I still #WearAMask in elevators, trains, planes, buses, pharmacies and supermarkets!
Outbreak: #COVID-19
Facility: Albright Manor
Facility Type: LTC Home
Unit/Floor/Area: 2 North East
Location: #Lincoln #Ontario
Facility Tracking Hash: #NRPH0030
Date: 2026-03-16
Public Health Unit: #Niagara Region Public Health Department
PHU Tracking Hash: #OnObNRPH
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Outbreak: #COVID-19
Facility: Chartwell Hollandview Trail
Facility Type: Retirement Home
Unit/Floor/Area: Facility Wide
Location: #Aurora #Ontario
Facility Tracking Hash: #YRPH0005
Date: 2026-03-17
Public Health Unit: York Region Public Health
PHU Tracking Hash: #OnObYRPH
Click or follow tracking hashtags to see data for individual facilities or a specific public health unit.
Schätzung Infektionsinzidenzen für Zürich aufgrund Kalibrierung der Abwasserprävalenzen Werdhölzli, Daten bis 15. März 2026:
Inzidenz ~50.
Ca. jede 2'000. Person infiziert sich pro Woche.
Tom Kindlon
Bich Nguyen
Nikolas Kozloff
Grace O'Malley
datum (n=1)
Angus Andrea Grieve-Smith
Ontario Outbreak Information
Dominik Steiger
diana 🏳️⚧️🦋🌱