“This work demonstrates the influential role of the cellular milieu on cellular organization and highlights glutamate as a modulator of intermolecular clustering interactions.”

Excellent first preLight post written by Erich Sohn covering work from Mrityunjoy Kar and colleagues #PappulabWashU, #SeidelLab #KnowlesLabCamb #HymanLab

#preLight 👉 https://prelights.biologists.com/highlights/glutamate-helps-unmask-the-differences-in-driving-forces-for-phase-separation-versus-clustering-of-fet-family-proteins-in-sub-saturated-solutions-v3/

#preprint #fet #fus #llps #condensate #glutamate #microscopy

Presenting a model for proteasome condensate formation in which shuttle factors play a critical role. ↔ 💧

Kenrick Waite and team #KUMedCenter show that shuttling factors Rad23 and Dsk2 contribute to the localization of proteasomes in condensates - a process that Ddi1 counteracts. #preprint

#preLight by Aniruddha Das 👉 https://prelights.biologists.com/highlights/proteasome-condensate-formation-is-driven-by-multivalent-interactions-with-shuttle-factors-and-k48-linked-ubiquitin-chains/

#proteasome #yeast #condensate

Referenced link: https://phys.org/news/2023-01-interfaces-play-important-role-condensate.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-01-interfaces-play-important-role-condensate.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1611439827576098820#m

Interfaces play important role in #condensate behavior @wustl @NatureComms https://www.nature.com/articles/s41467-022-35370-7 https://phys.org/news/2023-01-interfaces-play-important-role-condensate.html