🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦠 Could algorithms help us outpace evolving superbugs?

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics

🧱 What if activation and inhibition are not about binding but about motion?

🔗 Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines

🤯 What if most “biological insights” are just mixed-up signals we never untangled?

🔗 Integrative Learning of Disentangled Representations from Single-Cell RNA-Sequencing Datasets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0015

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SystemsBiology #Genomics #Bioinformatics #ComputationalBiology #AIinBiology #SingleCell #MachineLearning #DataScience #LifeSciences

🧬 Can we map the cascade of gene activity that guides cells through differentiation?

🔗 Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0007

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SingleCell #Genomics #Bioinformatics #SystemsBiology #GeneExpression #ComputationalBiology

🧬 Bioinformatics - Feb 2026

• Microbial dispersal and gene flow identified as key drivers of microbiome structure
• 22-protein panel distinguishes multiple sclerosis from other inflammatory diseases
• LUMI-lab autonomously synthesized 1,700+ lipid nanoparticles for mRNA delivery
• 134 mutational signatures identified across 16 cancer types
• Improved polygenic risk scores for breast cancer in African-ancestry women

https://pir.sh/pzy1b5yglv

#Bioinformatics #ComputationalBiology #Genomics

Bioinformatics Research Summary February 2026 - Summarized Science

Summary of key Bioinformatics publications highlighting major findings, clinical relevance, and emerging research trends.

🎉 Registration for ECCB 2026 is now open!
We are excited to welcome the European #ComputationalBiology & #Bioinformatics community to Geneva (31 Aug–4 Sept 2026).

Organized by SIB, #ECCB2026 will bring together researchers from around the world for five days of science, collaboration, and inspiration.

👉 More info: https://eccb2026.org/registration-information

⏰ Early bird until 31 March

Current open calls :
🔹 Proceedings papers until 16 March
🔹 Highlight talks & posters until 20 April

#GenevaLovesData