⚛️ Can we design drugs that stabilize biomolecular interactions instead of blocking them?

🔗 In Silico Analysis of Potential Stabilizer Binding Sites at Protein–RNA Interfaces. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0016

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #DrugDiscovery #ComputationalBiology #RNA #MolecularBiology #Bioinformatics #DrugDesign #SystemsBiology #MedicinalChemistry

Cell Painting is a scalable, image-based cellular profiling method that utilizes fluorescent dyes and artificial intelligence to measure thousands of molecular and structural changes in human cells following chemical exposure.
#Toxicology #Pharmacology #CellBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/03/phar03312601.html
Scalable cell imaging method could help make drug safety testing faster, cheaper

Researchers show that Cell Painting, an image-based cell profiling method, can reveal details of how drug candidates and other chemicals may harm cell

🚀 350+ participants already registered for #ECCB2026 ! Today is your last chance to join them at the early-bird rate.

From multi-omics to gene–disease discovery, genomic LLMs in practice, to connecting biological data with AI systems, this year’s most 3 popular tutorials highlight the growing impact of AI and data science across life sciences.
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⏰ That moment when you realize early-bird registration for #ECCB2026 ends… tomorrow.

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#GenevaLovesData #Bioinformatics #ComputationalBiology #ScientificConference #LifeSciences

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦠 Could algorithms help us outpace evolving superbugs?

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics

🧱 What if activation and inhibition are not about binding but about motion?

🔗 Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines