Managed to meet the March deadline of the #CAHRA2025 #CompHet #CryoEM challenge and submit something!

I only had time to do a very quick pass, but am very much looking forward to some feedback because it is an interesting dataset with several challenging aspects.

Currently reading a yuri #manga called Handsome Girl and Sheltered Girl about two college students dating. It involved gender confusion as the hook; the "handsome" girl is a little tomboyish and Sheltered Girl perceives [her] as a man and wants to date "him". Tomboy isn't opposed on principle but realizes Sheltered Girl think's she's a he. Tomboy doesn't "out" herself but struggles to find a "right time" that of course keeps getting thwarted for the sake of comedy. #CompHet is a thing so it could also be Tomboy's lesbian awakening, too, because in her inner monologue she keeps protesting "but we're both GIRLS!" yet doesn't seem to mind dating Sheltered Girl. Sheltered girl is too head over heels in love to question Tomboy's gender, hijinks ensue.

My first impression is that the heterogeneity isn't going to be the biggest challenge. I'm already pulling my hair over symmetry and anisotropy problems. 🙃

#CAHRA2025 #CompHet #CryoEM

Pretty excited about this "2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms" #CAHRA2025
https://heterogeneity.notion.site/challenge

I started looking at the compositional heterogeneity challenge (#CompHet), some very weird things in there. Curious to figure out what this is. Can't wait to get maps good enough for identification with ModelAngelo.

Are you also doing it @waldo ? 😀

#CryoEM

CAHRA 2025: Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms

A community-wide data processing challenge for cryo-electron microscopy.

heterogeneity on Notion
Compcomphet #blog entry by The B+ Squad with clear takedown of #comphet from a #bisexual angle https://www.patreon.com/posts/compcomphet-125602024

I'm seeing a lot of discussion around comphet (compulsory heterosexuality), which is amazing, but a LOT of it is straying into biphobia and that's fucking disappointing.

Do better.

#queer #comphet #bi #pan #sexuality #lgbtiqa

Episode ninety-four is up now! Today's song is Good Luck, Babe! by Chappell Roan.

I discuss the complex queer themes explored in the lyrics, and the absolutely gorgeous vocals that deliver them.

https://www.youtube.com/watch?v=hXOFJU6DGDo

#podcast #dailypodcast #pigeon #pigeonsongspod #music #songs #goodluckbabe #chappellroan #lesbian #sapphic #comphet

Good Luck, Babe! - Pigeon's Song of the Day (31/07/2024)

YouTube
Stephen Crowder and the Conservative Crusade Against No-Fault Divorce

Steven Crowder is part of a growing right-wing chorus calling for an end to modern divorce laws

Rolling Stone
The disgust, confusion, anxiety, amusement, horror, etc with which many vanilla ppl react to various kink/fetish interests and activites in some ways mirror feelings I've had towards PIV sex, to use myself as an example. This is, when handled maturely, completely fine on all sides! The problems come when some activities are compulsory and others are mocked, stigmatized, erased, and criminalized
#sex #kink #fetish #queer #lgbt #bodilyautonomy #righttosex #bdsm #compulsoryheterosexuality #comphet