Heading back from the annual TheRaCil meeting π
Great reports, fruitful discussions, novel ideas and an amazing evening on the Seine in Paris.
Special thanks to Sophie and the team in Paris for two productive and very valuable days!
π£ Exciting update from the Nephrolab 
Cologne:
This preprint marks our debut in the BBS research area, presenting work of Emilia KieckhΓΆfer on cystic kidney disease in Bbs8 and potential mechanisms.
A heartfelt thank you to Helen May-Simera and her team, along with all other contributors, for their invaluable support!
https://www.biorxiv.org/content/10.1101/2024.03.07.583949v1
#BBS #Ciliopathy #RareDisease #Nephrology #Kidney #Nephrolab #Cilia #BardetBiedl #Science #CellBiology #BBS8
@cilia
Cilia play critical roles in cell signal transduction and organ development. This study shows that the Cep131-Cep162 module near the axoneme and the Cby-Fam92 module near the membrane work together to regulate the localization of the highly conserved ciliopathy protein Cep290 at the basal body to initiate ciliogenesis.
After a wonderful kick-off meeting β¦βͺof TheRaCil time to chill by Copenhagenβs canals π¬οΈπ₯Άππ¬οΈ
@cilia #cilia #Ciliopathy #RareDiseases #Zilien #Nephrology #Nephrologie
Organ laterality of vertebrates is specified by accelerated asymmetric decay of Dand5 mRNA mediated by Bicaudal-C1 (Bicc1) on the left side, but how is this regulated? Structure-function analysis of the ciliopathy proteins ANKS3 and ANKS6 suggests a dual role in either inhibiting or promoting the binding of Bicc1 to its own transcripts and to client mRNAs.
Thrilling times! 
Following the exhilarating pre-kickoff rendezvous with #Theracil in Paris, today marked the electrifying pre-kickoff of Workpackage 2 in Cologne
Our marathon discussions have truly borne fruit, propelling us forward with absolute clarity!
A huge thanks to everyone who journeyed to Cologne or powered up zoom to join us!
Ready, set, let the journey commence!!! ππ
#TheraCil #Ciliopathy #RareDisease #Collaboration #Science #Cilia #Sciencemastodon
@cilia
Register now for the amazing hybrid centrosome conference in Istanbul, hosted by Elif Nur Firat-Karalar!
Sharing this announcement on the fediverse. Unsure if Elif has joined Mastodon yetβ¦
Some of us might see this as the basal body meeting π
@cilia
#Centrosome2023
#cilia #centrosome #centriole #Embo #EmboWorkshop #Science #zilien #RareDisease #ScienceMastodon #Zentrosom #developmentalbiology #biology @nephrology #CellBiology #Ciliopathy
π£ Today the very last invoice of "EMBO Cilia2022" in was finally transferred and so this chapter closes. 
A final huge THANK YOU to ALL who made this meeting such a success.
Looking forward to meeting you in Dublin at Cilia2024 π
#Cilia2022 #CIlia2024 @cilia #EMBOCilia2022
@UniKoeln #science #ciliopathy #RareDisease
Wonderful!
For more sleeps ...
π
#cilia #ciliopathy #RareDiseases #centrosome #centriole #CellBiology #DevelopmentalBiology #DevBio
@cilia
PLOS Biology
Bernhard Schermer