Scientific FrontlineOct 7
UQ researchers have led the first randomized trial across 6 countries to examine a new #antibiotic, #cefiderocol in the treatment of life-threatening, drug-resistant #infections. #Pharmaceutical #sflorg
https://www.sflorg.com/2025/10/phar10072501.html
Clinical trial marks key milestone in fight against antibiotic resistance

Infections with antibiotic-resistant bacteria cause a significant burden of disease worldwide.

Gabriele PollaraSep 3, 2023

We may be losing #cefiderocol far sooner than we hoped.

Timely meta-analysis. Look at those #resistance rates in #carbapenem resistant Enterobacterales!

#microbiology #AMR #antibiotics #antibiotic #CriticalCare #Pseudomonas #Acenitobacter #infectiousdiseases #IDMastodon #medicine

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00413-5/fulltext?dgcid=raven_jbs_aip_email

JAC-AMRAug 22, 2023
Curious to know more about the #Netflix model for antimicrobials? The SMASH study in the UK explored the views of infection consultants in England on the novel antimicrobial subscription model for #cefiderocol and #ceftazidime-avibactam that started in July 2022. Are delinked funding models the solution to the dry antimicrobial production pipeline?
https://doi.org/10.1093/jacamr/dlad091
#JACAMRNews
Exploring the views of infection consultants in England on a novel delinked funding model for antimicrobials: the SMASH study

AbstractObjectives. A novel ‘subscription-type’ funding model was launched in England in July 2022 for ceftazidime/avibactam and cefiderocol. We explored the vi

OUP Academic
Gabriele PollaraNov 24, 2022

Important we consider how resistance is selected for these new antibiotics. Need to make them last!

#AMR #cefiderocol #antibiotics #IDMastodon #MedMastodon #cysticfibrosis #antimicrobialstewardship #WAAW2022

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(22)00586-9/fulltext?dgcid=raven_jbs_aip_email

Scientific EuropeanNov 20, 2022

#cefiderocol A New #Antibiotic for Treating Complex and Advanced #UrinaryTractInfections ... | A newly discovered antibiotic follows a unique mechanism in fighting #drugresistant #bacteria responsible for #UTI Antibiotic resistance is a major #global threat to #healthcare Antibiotic...

https://www.scientificeuropean.co.uk/medicine/cefiderocol-a-new-antibiotic-for-treating-complex-and-advanced-urinary-tract-infections/

Cefiderocol: A New Antibiotic for Treating Complex and Advanced Urinary Tract Infections

A newly discovered antibiotic follows a unique mechanism in fighting drug-resistant bacteria responsible for UTIs. Antibiotic resistance is a major global th

Scientific European
Gabriele PollaraNov 18, 2022

A bit more real-world data on #cefiderocol use.

Outcomes not great but equally it's used in patients with poor expected outcomes. Accurate susceptibility testing clearly also remains an issue. #WAAW2022 #AMR #antibiotics

https://www.sciencedirect.com/science/article/pii/S1198743X22005717