Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0
#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics
Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0
#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics
π¦ I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !
If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner
https://genomic.social/@nf_core@mstdn.science/109868600236675816 𧡠[1/2]
Pipeline release! nf-core/funcscan v1.0.0 ((Meta-)genome screening for functional and natural product gene sequences) See the changelog: https://github.com/nf-core/funcscan/releases/tag/1.0.0
Finishing up a journal article review assignment and found this great review of natural products as anticancer therapeutics.
#cancer #naturalproducts #synbio #bioinformatics #biosyntheticgeneclusters #drugdiscovery
Natural products have multifarious bioactivities against bacteria, fungi, viruses, cancers and other diseases due to their diverse structures. Nearly 65% of anticancer drugs are natural products or their derivatives. Thus, natural products play significant roles in clinical cancer therapy. With the development of biosynthetic technologies, an increasing number of natural products have been discovered and developed as candidates for clinical cancer therapy. Here, we aim to summarize the anticancer natural products approved from 1950 to 2021 and discuss their molecular mechanisms. We also describe the available synthetic biology tools and highlight their applications in the development of natural products.
nf-core
James Fellows Yates
Ron Masse