Schizophrenia study finds new biomarker, drug candidate to treat symptoms
#HackerNews #Schizophrenia #Biomarker #DrugResearch #MentalHealth #Neuroscience
A new Northwestern University study in humans and mice has discovered a novel biomarker of schizophrenia that could also serve as a new drug candidate to treat the cognitive symptoms of the disorder. Schizophrenia affects .5% of the world’s population, including about two million people in the U.S.
`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1
#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain
In Folge B unserer Serie ABC der Genetik sprechen wir über Biomarker: messbare biologische Hinweise, die dabei helfen können, Krankheiten besser einzuschätzen oder Behandlungen gezielter zu planen. Gemeinsam mit der Genetik-Expertin Prof. Dr. Julia Schulze-Hentrich klären wir folgende Fragen: Was sind Biomarker? Wie unterscheiden sich klassische von genetischen Biomarkern? Wo werden sie in Diagnostik, Prävention und Therapie eingesetzt? Und wo liegen ihre Grenzen?
😅 Don't sweat it: New device detects sweat biomarker at minimal perspiration rate
https://medicalxpress.com/news/2025-09-dont-device-biomarker-minimal-perspiration.html
#sweat #sensors #wearables #biomarker #stress #diagnostics #research
Available on demand, in abundance and containing multiple biomarkers, sweat is an increasingly appealing medium for monitoring health, according to researchers at Penn State. But not everyone—especially critically ill patients—can build up enough sweat to provide a robust enough sample for current analysis techniques.
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