ENG: In women with chronic pain syndromes, an excellent real-life Brazilian study of full-spectrum cannabis extracts with tailored dosages found improvements in pain relief, cognitive function, motor abilities, professional activities & ability, irritability, anxiety, melancholy, fatigue & sleep quality

ESP: En mujeres con síndrome de dolor crónico, un excelente estudio brasileño en el mundo real sobre extractos de cannabis de espectro completo (flor de cannabis, no fibras de cáñamo) y dosis personalizadas, encontró mejoras en el alivio del dolor, la función cognitiva, las habilidades motoras, las actividades y capacidades profesionales, la irritabilidad, la ansiedad, la melancolía, la fatiga y la calidad del sueño.

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1538518/full

#pain #menstrual #menstrualcycle
#autoinmunes #autoinmunedisease
#ChronicIllnesses #chronicpain
#cannabis #Cannabinoids #thc
#cannabinoide #EfectoSéquito
#dolor #mujeres #saludmental
#medicalcannabis #marijuana
#cannabismedicinal #cbd

Frontiers | Full-spectrum cannabis extracts for women with chronic pain syndromes: a real-life retrospective report of multi-symptomatic benefits after treatment with individually tailored dosage schemes

Chronic pain syndromes (CPS) are debilitating conditions for which cannabis extracts and cannabinoids have shown promise as effective treatments. However, ac...

Frontiers

"The #cannabis plant contains hundreds of chemical compounds. Among them #Cannabinoids , #flavonoids and #terpenes are the most relevant. Delta-nine #THC and #CBD are the most abundant cannabinoids and therefore the most studied.

However there are other minor cannabinoids such as delta-eight thc, #thca , thcv, cbg, #cbn , cbc which have been investigated to have therapeutic value (Izzo et al. 2009).

Although the compounds may have therapeutic effects taken alone (as in HEMP-derived isolate), their combined action when present together in whole plants (actually complete flower) extracts, is GREATER than the sum of their individual effects (up to 6x more potent according to recent studies). This enhanced and synergistic response is known as the #entourageeffect .

The combined action of cannabinoids and other molecules in the plant may present clinical advantages such as lower adverse effects and greater efficacy on the therapeutical management of several conditions, such as #anxiety , #depression , #pain , #inflammation , #cancer and bacterial / fungi #infectiousdiseases

If other forms of healing interest you, beyond masking symptoms with synthetic proprietary mono-molecules, check this link for a more up-to-date text on cannabis and the entourage effect:
https://leafwell.com/blog/entourage-effect

#healthcare #medical #healthscience #marijuananews #marijuana #weed #naturalist
#cannabismedicinal #herbalism
#solarpunk #chronicillness #regenerativemedicine #pain
#weed #autoinmunedisease #medicalcrisis #herbalmedicine

The Entourage Effect: What Is It, and How Does It Work?

Cannabis works best as a whole plant. This is called the Entourage Effect. Discover how using cannabis holistically can improve medical benefits.

Leafwell

"There may be instances where only a single cannabinoid (isolate - as in hemp extract) is needed, but in general, cannabinoids work best together and deliver the entourage effect. Pinene and CBD can mitigate some of THC’s adverse effects on short-term memory. A broad spectrum of cannabinoids is also ideal for treating cancer, as they work synergistically to boost their antitumor properties. Combining cannabinoids and terpenoids ( as in complete spectrum FLOWER) can also improve their usefulness as anti-inflammatories and painkillers."
https://leafwell.com/blog/entourage-effect

Friends, lets take care of our bodies and minds too (not only our computers and software). Self-care is a form of resistance in these trying times. Synthetic medication is always a double-edged sword.

I'v been helping my family with this ancestral medicine for almost 6 years now. Let me know if you have any doubts on how to best use it for your condition and metabolism. No sales or distribution.

#health #medical #healthscience #marijuananews #marijuana #medicalcannabis #weed
#regenerativemedicine #cbd
#thc #cbn #thca #pain #chronicillness #chronic
#autoinmunedisease #autoinmume #medicalcrisis
#solarpunk #naturalist #herbalmedicine #herbalism

The Entourage Effect: What Is It, and How Does It Work?

Cannabis works best as a whole plant. This is called the Entourage Effect. Discover how using cannabis holistically can improve medical benefits.

Leafwell
Blood DNA virome associates with autoimmune diseases and COVID-19.
#Autoinmuninity #AutoinmuneDisease #COVID-19 #HHV-6 #Anellovirus #SLE
https://www.nature.com/articles/s41588-024-02022-z
Blood DNA virome associates with autoimmune diseases and COVID-19 - Nature Genetics

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Nature

Prevalence and Risk Factors of Post-Acute Sequela of COVID-19 in Adults with Systemic Autoimmune Rheumatic Diseases.

#LongCovid #AutoinmuneDisease

https://www.jrheum.org/content/early/2024/06/24/jrheum.2023-1212

Prevalence and Risk Factors of Post-Acute Sequela of COVID-19 in Adults with Systemic Autoimmune Rheumatic Diseases

Objective Incidence and manifestations of post-acute sequelae of COVID-19 (PASC) are poorly defined among immunosuppressed populations. We reported, phenotyped, and assessed risk factors for PASC in adults with systemic autoimmune diseases. Methods Persons ≥18 years with systemic autoimmune diseases were recruited into a national, prospective cohort of SARS-CoV-2 vaccination between 12/2020-4/2021. Serial surveys assessed vaccination status, SARS-CoV-2 infection incidence, and disease flares. Participants reporting SARS-CoV-2 infection received a questionnaire assessing symptom duration, severity, and quality of life (QoL) impact; PASC was defined as ≥1 symptom persisting for >12 weeks. PASC syndromes were mapped via overlapping symptom domains. Characteristics were compared between participants who did versus did not report PASC. Results Among 1615 participants, 590 (36.5%) reported SARS-CoV-2 infection and were sent PASC surveys, 299 (50.7%) of whom responded >12 weeks following reported infection. Respondents were 1.62% female, 90.2% white, median (IQR) age 48(40-60) years with median (IQR) 3 (2-3) vaccine doses at time of first infection. Common diagnoses included inflammatory arthritis (38.5%) and inflammatory bowel disease (14.4%). 89/299 (29.8%) reported PASC, with the most reported symptom domain being neurological/psychological (83.1%); 84% reported an impact on QoL. Participants with PASC reported lower number of preceding vaccines (median [IQR] 2[2-3] versus 3[2-3]; p<0.001) and more reinfections (16.9% versus 5.7%; p=0.004). Conclusion 29.8% of persons with systemic autoimmune disease in a large real-world cohort reported PASC, often affecting QoL. Preceding vaccination may reduce PASC, whereas multiple infections may increase risk, supporting ongoing booster vaccine campaigns and efforts to limit breakthrough infections.

The Journal of Rheumatology
Nearly 30% of patients with autoimmune disease report long COVID after infection

Among patients with systemic autoimmune disease in a large, real-world cohort, 29.8% reported long COVID, with frequent impacts to quality of life, following infection, according to data published in The Journal of Rheumatology. “People with autoimmune conditions such as lupus, rheumatoid arthritis and inflammatory bowel disease endure higher rates of severe acute COVID-19 related to