Matt WillemsenMar 6, 2024
Flashing Lights And a Clicking Sound Cleared Toxic Proteins in Alzheimer's Mice
https://www.sciencealert.com/flashing-lights-and-a-clicking-sound-cleared-toxic-proteins-in-alzheimers-mice #brain #alzheimers #GammaWaves #cleaning #waste #GlymphaticSystem #mice #aquaporin—4
Flashing Lights And a Clicking Sound Cleared Toxic Proteins in Alzheimer's Mice

Could Alzheimer's disease one day be treated by flashes of light and clicks of sound? Scientists have now demonstrated how stimulating high-frequency brain waves in mice can clear out the amyloid protein clumps associated with Alzheimer's.

ScienceAlert
Scientific FrontlineDec 27, 2023
#Aquaporin (Aqp) 10 water channels in #humans allow the free passage of water, glycerol, urea, and boric acid across #cells. However, Aqp10.2b in #pufferfishes allows only the passage of water and glycerol and not urea and boric acid.
#Biology #sflorg
https://www.sflorg.com/2023/12/bio12272301.html
The Evolutionary Timeline of Diminished Boric Acid and Urea Transportation in Aquaporin 10

Aquaporins (Aqps) are proteins that form water channels in the membranes of living cells

CellBioNewsDec 22, 2023

The #evolutionary timeline of diminished #boric_acid and #urea transportation in #aquaporin 10.

#genomic #phylogeny

https://phys.org/news/2023-12-evolutionary-timeline-diminished-boric-acid.html

The evolutionary timeline of diminished boric acid and urea transportation in aquaporin 10

Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells. However, Aqp10.2b in pufferfish allows only the passage of water and glycerol and not urea and boric acid.

Phys.org
katch wreckDec 5, 2023

"In a biological context, sucrose transport could constitute a novel element of plant saccharide-transporting machinery. Phylogenomic analyses of 164 Viridiplantae and 2993 Archaean, bacterial, fungal, and Metazoan aquaporins rationalized solute poly-selectivity in NIP3 sub-clade entries and suggested that they diversified from other sub-clades to acquire a unique specificity of saccharide #transporters"

https://www.jbc.org/article/S0021-9258(23)02438-9/fulltext

#aquaporin

JIPBOct 25, 2023
#Cassava is an important source of #food #carbohydrates in the tropics, and #magnesium is vital for #plant #growth and #development.
Read on to find out how these two things go together!
https://doi.org/10.1111/jipb.13552
@wileyplantsci
#JIPB #aquaporin #Xenopus #PlantScience #PlantSci #botany
JIPBSep 1, 2023
#Cassava is an important source of #food #carbohydrates in the tropics, and #magnesium is vital for #plant #growth and #development. Find out how these two things go together in this new #JIPB paper!
https://doi.org/10.1111/jipb.13552
@wileyplantsci
#aquaporin #Xenopus #PlantScience #BOtany
Lukas VFN 🇪🇺Mar 29, 2023

How the ancestors of today's marine #fishes conquered the oceans https://phys.org/news/2023-03-ancestors-today-marine-fishes-conquered.html

Functional evolution of clustered #aquaporin genes reveals insights into the oceanic success of teleost eggs https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msad071/7083725

"They uncovered a cluster of water channel genes that only exists in teleost #fishes. The genes allow water to flow across cell membranes and are specifically expressed in the outer membranes of the maturing egg."

How the ancestors of today's marine fishes conquered the oceans

An international team led by researchers from IRTA at the IBB-UAB and the University of Bergen have identified a unique set of genes that allows marine teleost fishes to hydrate their eggs so that they float and disperse for survival in the ocean. The discovered mechanisms shed new light on the evolution of this group of fishes, to which almost all modern marine fishes belong and whose ancestors ventured from freshwater to the saline domain.

Phys.org
Lukas VFN 🇪🇺Nov 22, 2022

Quick-closing valve allows fish to rapidly regulate the water in their cells
https://phys.org/news/2022-11-quick-closing-valve-fish-rapidly-cells.html

High-resolution structure of a #fish #aquaporin reveals a novel extracellular fold https://www.life-science-alliance.org/content/5/12/e202201491

By studying the #aquaporins in the cells of the #ClimbingPerch Anabas testudineus, which sometime climb out of the water and spend time on land, researchers have identified a water channel that appears to have a unique quick-closing valve.

Quick-closing valve allows fish to rapidly regulate the water in their cells

Regulating the fluid balance in cells is vital in all living things. When insufficient water is being transported via the cell membrane, cells can use their aquaporins—also known as water channels—that open and close to remedy this. Researchers at the University of Gothenburg recently identified a water channel in a fish with what appears to be a unique quick-closing valve. Ultimately, this discovery could be significant in the development of drugs to treat cancer and Alzheimer's disease.

Phys.org