How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @PLOSBiology https://plos.io/46tDxny

New #ISEPpapers! Phylogenomic diversity of archigregarine apicomplexans https://royalsocietypublishing.org/doi/full/10.1098/rsob.240141

"#Gregarines are a large and diverse subgroup of #Apicomplexa, a lineage of obligate animal #symbionts including pathogens such as #Plasmodium, the #malaria parasite. Unlike Plasmodium, however, gregarines are poorly studied, despite the fact that as early-branching #apicomplexans they are crucial to our understanding of the origin and evolution of all apicomplexans and their parasitic lifestyle."

#Apicomplexans need specialized structures to invade host cells & replicate. @petersmback @GEWard14 @ToxInLA &co show that alveolin protein IMC6 is crucial for maintaining cellular morphology, invasion & successful replication in #Toxoplasma #PLOSBiology https://plos.io/3BgjxaE
Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication

Picomplexan parasites require specialized structures like the inner membrane complex to invade host cells and replicate. This study shows that the alveolin protein IMC6 is crucial for maintaining cellular morphology, invasion and successful replication in Toxoplasma gondii.

Coral-infecting #parasites in cold marine ecosystems https://www.cell.com/current-biology/abstract/S0960-9822(24)00323-3 #protists #microbes by Morelia Trznadel et al.

"#CoralReefs are a #biodiversity hotspot, and the association between coral and intracellular #dinoflagellates is a model for #endosymbiosis. Recently, #corals and related #anthozoans have also been found to harbor another kind of endosymbiont, #apicomplexans called #corallicolids."

Diversity is key for understanding #Apicomplexans & #Dinoflagellates
Check this out: https://cell.com/trends/parasitology/fulltext/S1471-4922(22)00221-5. It is a summary of topics discussed at CJM4, new tools and technologies driving the opportunities for discovery and understanding in #Myzozoa #protists #parasites #endosymbiosis