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🌍 One Health - Apr 2026

• Slaughtered swine identified as hotspots for antimicrobial-resistant E. coli
• Soil microbial diversity reduces prevalence of human bacterial pathogens
• Non-human A. baumannii shows greater diversity, raising public health concern
• 1.5°C lifestyle changes yield co-benefits for human and ecosystem health

https://pir.sh/xMNdAQMd6e

#OneHealth #Antimicrobials

One Health Strict Research Summary April 2026 - Summarized Science

Summary of key One Health Strict publications highlighting major findings, clinical relevance, and emerging research trends.

Alexander J. Stein Nov 4, 2025

The development of new #antibiotics will not be enough to curb the rise in #deaths from drug-resistant #infections, for which the misuse & overuse of #antimicrobials in human medicine & #agriculture are the main drivers… (1/2) doi.org/10.1038/d415... #health #AMR

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Alexander J. Stein Oct 27, 2025

(2/3) The use of antibiotics in #farming is widespread & indiscriminate: 73% of all #antimicrobials sold globally are used in #animals raised for food. This enormous overuse leads to a rise in antibiotic-resistant pathogens, i.e. #infections that were once easily… www.theguardian.com/commentisfre...

Beef, pork, chicken: the world loves cheap meat. If people knew what really goes in it, that love affair would be over

Antibiotic use in farming is now rampant. How meat is produced in China may mean the drugs you need here won’t work, says Prof Devi Sridhar, chair of global public health at the University of Edinburgh

The Guardian

Alexander J. Stein Oct 10, 2025

#Germany: The amount of #antibiotics dispensed in veterinary medicine increased by 34 tons in 2024. A total of 562 tons of antibiotics—incl. “highest priority critically important #antimicrobials for human medicine”—were dispensed to animals… (1/2) www.bvl.bund.de/SharedDocs/P...

Pressemitteilungen - Antibioti...

BVL - Pressemitteilungen - Antibiotikaabgabe in Tiermedizin leicht gestiegen

Die Menge der in der Tiermedizin abgegebenen Antibiotika ist in Deutschland im Jahr 2024 leicht gestiegen. Laut Bundesamt für Verbraucherschutz und Lebensmittelsicherheit (BVL) wurden insgesamt 562 Tonnen Antibiotika an Tierärzte und weitere Empfänger abgegeben. Das ist ein Plus von 34 Tonnen (6,4 %) gegenüber dem Vorjahr. Im Vergleich zu 2011, dem ersten Jahr der Erfassung, beträgt der Rückgang 67 Prozent.

Alexander J. Stein Mar 6, 2025

Use of #antimicrobials in humans & #animals can lead to the spread of #microorganisms that are resistant to them, rendering #antimicrobial treatment ineffective and posing a serious risk to #PublicHealth. Resistance to certain antimicrobials… (1/x) www.efsa.europa.eu/en/plain-lan... #health

Antimicrobial resistance in zo...

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PLOS Biology Nov 19, 2024

Niche-targeting of #antimicrobials. @EmmaGlass33 @papinsysbio &co use a computational data-driven approach to #DrugTarget discovery by identifying #metabolic signatures of diverse #pathogens conserved within body sites. Proof-of-principle with stomach-specific pathogens #PLOSBiology https://plos.io/40TewzH

Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens

The emergence of resistance to traditional antimicrobials increases the need to develop innovative approaches to understanding pathogen function. This study uses a computational data-driven approach to drug target discovery by identifying metabolic signatures of diverse pathogens conserved within body sites. In vitro validation shows that such site-targeted antimicrobials can effectively inhibit stomach-specific pathogens.

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David Wakeham Nov 13, 2024

Environmental Changes 🌡️🦠

The rise in temperatures and alterations in precipitation patterns are leading to several significant consequences:

• Accelerated #bacterial growth rates

• Extended survival of #pathogens in the #environment

• Changes in the geographical #distribution of #diseases

• Altered effectiveness of #antimicrobials

#EnvironmentalAMR #ClimateEffects

https://doi.org/10.1016/j.scitotenv.2021.147823

3/n

Evaluation of private well contaminants in an underserved North Carolina community

On-site sewage treatment systems can be an important source of antibiotic resistant bacteria and organic micropollutants into adjacent groundwater. Du…